methyl 1β-<<1-(methoxycarbonyl)ethenyl>oxy>-4α-hydroxycyclohex-2-ene-1-carboxylate

Base Information

Chemical Name:methyl 1β-<<1-(methoxycarbonyl)ethenyl>oxy>-4α-hydroxycyclohex-2-ene-1-carboxylate
CAS No.:115162-84-0
Molecular Formula:C₁₂H₁₆O₆
Molecular Weight:256.255
Hs Code.:

Synonyms:methyl 1β-<<1-(methoxycarbonyl)ethenyl>oxy>-4α-hydroxycyclohex-2-ene-1-carboxylate

Suppliers and Price of methyl 1β-<<1-(methoxycarbonyl)ethenyl>oxy>-4α-hydroxycyclohex-2-ene-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 1β-<<1-(methoxycarbonyl)ethenyl>oxy>-4α-hydroxycyclohex-2-ene-1-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 1β-<<1-(methoxycarbonyl)ethenyl>oxy>-4α-hydroxycyclohex-2-ene-1-carboxylate

There total 9 articles about methyl 1β-<<1-(methoxycarbonyl)ethenyl>oxy>-4α-hydroxycyclohex-2-ene-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 115162-83-9
methyl 1β-<<1-(methoxycarbonyl)ethenyl>oxy>-4α-acetoxycyclohex-2-ene-1-carboxylate

: 115162-84-0
methyl 1β-<<1-(methoxycarbonyl)ethenyl>oxy>-4α-hydroxycyclohex-2-ene-1-carboxylate

Guidance literature:: With sodium methylate; In methanol; at 0 ℃; for 1h;
DOI:10.1021/jo00249a022

Reference yield:

: 30810-15-2
methyl cyclohexa-1,3-diene-1-carboxylate

: 115162-84-0
methyl 1β-<<1-(methoxycarbonyl)ethenyl>oxy>-4α-hydroxycyclohex-2-ene-1-carboxylate

Guidance literature:: Multi-step reaction with 7 steps

1: 99 percent / m-CPBA / CH₂Cl₂ / 1.) -70 deg C, 30 min, 2.) RT, 2 h

2: 73 percent / NaBH₄ / methanol / 4 h / 0 °C

3: 70 percent / H₂O₂ / acetone / 1.) 0 deg C, 2 h, 2.) RT, 24 h

4: 91 percent / Et₃N / CH₂Cl₂ / 20 h / Ambient temperature

5: Rh₂(n-Oct)4 / benzene / 24 h / 80 °C

6: 1.) LiN(SiMe₃)2 / 1.) THF, - 65 deg C, 20 min, 2.) RT, 15 min

7: 68 percent / NaOMe / methanol / 1 h / 0 °C

With sodium tetrahydroborate; Rh₂(n-Oct)4; dihydrogen peroxide; sodium methylate; triethylamine; 3-chloro-benzenecarboperoxoic acid; lithium hexamethyldisilazane; In methanol; dichloromethane; acetone; benzene;
DOI:10.1021/jo00249a022

Reference yield:

: 115162-79-3
methyl 1β,4α-dihydroxycyclohex-2-ene-1-carboxylate

: 115162-84-0
methyl 1β-<<1-(methoxycarbonyl)ethenyl>oxy>-4α-hydroxycyclohex-2-ene-1-carboxylate

Guidance literature:: Multi-step reaction with 4 steps

1: 91 percent / Et₃N / CH₂Cl₂ / 20 h / Ambient temperature

2: Rh₂(n-Oct)4 / benzene / 24 h / 80 °C

3: 1.) LiN(SiMe₃)2 / 1.) THF, - 65 deg C, 20 min, 2.) RT, 15 min

4: 68 percent / NaOMe / methanol / 1 h / 0 °C

With Rh₂(n-Oct)4; sodium methylate; triethylamine; lithium hexamethyldisilazane; In methanol; dichloromethane; benzene;
DOI:10.1021/jo00249a022