Technology Process of 2-methyl-2-(3,4,5-trimethoxyphenylhydroxymethyl)-1,3-dithiane
There total 1 articles about 2-methyl-2-(3,4,5-trimethoxyphenylhydroxymethyl)-1,3-dithiane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
n-butyllithium;
In
tetrahydrofuran;
Ambient temperature;
DOI:10.1246/cl.1984.67
- Guidance literature:
-
Multi-step reaction with 6 steps
1: pyridine
2: N-chlorosuccinimide, aqueous aceton / 10 - 16 °C
3: 90 percent / TiCl4, pyridine / Ambient temperature
4: concentrated HCl / methanol / Heating
5: NaBH4 / methanol / 5 °C
6: 92 percent / triethylamine / methanol / 5 °C
With
pyridine; hydrogenchloride; sodium tetrahydroborate; N-chloro-succinimide; titanium tetrachloride; triethylamine; acetone;
In
methanol;
DOI:10.1246/cl.1984.67
- Guidance literature:
-
Multi-step reaction with 6 steps
1: pyridine
2: N-chlorosuccinimide, aqueous aceton / 10 - 16 °C
3: 90 percent / TiCl4, pyridine / Ambient temperature
4: concentrated HCl / methanol / Heating
5: NaBH4 / methanol / 5 °C
6: NaCl / dimethylsulfoxide; H2O / 140 °C
With
pyridine; hydrogenchloride; sodium tetrahydroborate; N-chloro-succinimide; titanium tetrachloride; acetone; sodium chloride;
In
methanol; water; dimethyl sulfoxide;
DOI:10.1246/cl.1984.67
