3-methoxyphenyl 3,4,6-tri-O-benzyl-2-deoxy-2-nitro-α-D-galactopyranoside

Base Information

• Chemical Name: 3-methoxyphenyl 3,4,6-tri-O-benzyl-2-deoxy-2-nitro-α-D-galactopyranoside
• CAS No.: 593260-92-5
• Molecular Formula: C₃₄H₃₅NO₈
• Molecular Weight: 585.654
• Mol file: 593260-92-5.mol

Synonyms:3-methoxyphenyl 3,4,6-tri-O-benzyl-2-deoxy-2-nitro-α-D-galactopyranoside

Chemical Property of 3-methoxyphenyl 3,4,6-tri-O-benzyl-2-deoxy-2-nitro-α-D-galactopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-methoxyphenyl 3,4,6-tri-O-benzyl-2-deoxy-2-nitro-α-D-galactopyranoside

There total 1 articles about 3-methoxyphenyl 3,4,6-tri-O-benzyl-2-deoxy-2-nitro-α-D-galactopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

O-methylresorcine (150-19-6) + 3,4,6-tri-O-benzyl-2-nitro-D-galactal (211621-55-5) → 3-methoxyphenyl 3,4,6-tri-O-benzyl-2-deoxy-2-nitro-α-D-galactopyranoside (593260-92-5)

Guidance literature:

With potassium tert-butylate; In tetrahydrofuran; toluene; at 20 ℃; for 0.5h;

DOI:10.1002/ejoc.200200712

Reference yield: 80.0%

3-methoxyphenyl 3,4,6-tri-O-benzyl-2-deoxy-2-nitro-α-D-galactopyranoside (593260-92-5) → 3-methoxyphenyl 2-amino-3,4,6-tri-O-benzyl-2-deoxy-α-D-galatopyranoside (593260-72-1)

Guidance literature:

With hydrogen; Raney nickel T₄; In ethanol; at 20 ℃; for 48h;

DOI:10.1002/ejoc.200200712

Reference yield:

3-methoxyphenyl 3,4,6-tri-O-benzyl-2-deoxy-2-nitro-α-D-galactopyranoside (593260-92-5) → 3-methoxyphenyl 2-acetamido-2-deoxy-α-D-galactopyranoside

Guidance literature:

Multi-step reaction with 2 steps

1: 80 percent / hydrogen / Raney nickel T₄ / ethanol / 48 h / 20 °C

2: hydrogen / Pd/C (10percent) / methanol; acetic acid / 3 h

With hydrogen; Raney nickel T₄; In methanol; ethanol; acetic acid;

DOI:10.1002/ejoc.200200712

upstream raw materials:

O-methylresorcine

3,4,6-tri-O-benzyl-2-nitro-D-galactal

Downstream raw materials:

3-methoxyphenyl 2-amino-3,4,6-tri-O-benzyl-2-deoxy-α-D-galatopyranoside