(3R)-3-[2-benzyl-6-(3,3-ethylenedioxy-2-pyrrolidinone-1-yl)-3-pyridyl]ethynyl-3-quinuclidinol

Base Information

Chemical Name:(3R)-3-[2-benzyl-6-(3,3-ethylenedioxy-2-pyrrolidinone-1-yl)-3-pyridyl]ethynyl-3-quinuclidinol
CAS No.:332132-79-3
Molecular Formula:C₂₇H₂₉N₃O₄
Molecular Weight:459.545
Hs Code.:

Synonyms:(3R)-3-[2-benzyl-6-(3,3-ethylenedioxy-2-pyrrolidinone-1-yl)-3-pyridyl]ethynyl-3-quinuclidinol

Suppliers and Price of (3R)-3-[2-benzyl-6-(3,3-ethylenedioxy-2-pyrrolidinone-1-yl)-3-pyridyl]ethynyl-3-quinuclidinol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3R)-3-[2-benzyl-6-(3,3-ethylenedioxy-2-pyrrolidinone-1-yl)-3-pyridyl]ethynyl-3-quinuclidinol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3R)-3-[2-benzyl-6-(3,3-ethylenedioxy-2-pyrrolidinone-1-yl)-3-pyridyl]ethynyl-3-quinuclidinol

There total 3 articles about (3R)-3-[2-benzyl-6-(3,3-ethylenedioxy-2-pyrrolidinone-1-yl)-3-pyridyl]ethynyl-3-quinuclidinol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 332135-07-6
2-benzyl-6-(3,3-ethylenedioxy-2-pyrrolidinone-1-yl)-3-pyridyl trifluoromethanesulfonate

: 160172-20-3
(R)-(+)-3-ethynyl-3-hydroxy quinuclidine

: 332132-79-3
(3R)-3-[2-benzyl-6-(3,3-ethylenedioxy-2-pyrrolidinone-1-yl)-3-pyridyl]ethynyl-3-quinuclidinol

Guidance literature:: With ammonium hydroxide; copper(I) iodide; triethylamine; tetrakis(triphenylphosphine)palladium ⁽⁰⁾; In methanol; hexane; ethyl acetate; N,N-dimethyl-formamide;

Reference yield:

: 332135-06-5
2-benzyl-6-(3,3-ethylenedioxy-2-pyrrolidinone-1-yl)-3-hydroxypyridine

: 332132-79-3
(3R)-3-[2-benzyl-6-(3,3-ethylenedioxy-2-pyrrolidinone-1-yl)-3-pyridyl]ethynyl-3-quinuclidinol

Guidance literature:: Multi-step reaction with 2 steps

1: dmap; triethylamine / dichloromethane; ethyl acetate

2: ammonium hydroxide; copper(I) iodide; triethylamine / tetrakis(triphenylphosphine)palladium ⁽⁰⁾ / methanol; hexane; ethyl acetate; N,N-dimethyl-formamide

With dmap; ammonium hydroxide; copper(I) iodide; triethylamine; tetrakis(triphenylphosphine)palladium ⁽⁰⁾; In methanol; hexane; dichloromethane; ethyl acetate; N,N-dimethyl-formamide;

Reference yield:

: 332135-05-4
2-benzyl-3-methoxymethyloxy-6-[(3S)-3-hydroxy-2-pyrrolidinone-1-yl]pyridine

: 332132-79-3
(3R)-3-[2-benzyl-6-(3,3-ethylenedioxy-2-pyrrolidinone-1-yl)-3-pyridyl]ethynyl-3-quinuclidinol

Guidance literature:: Multi-step reaction with 3 steps

1: toluene-4-sulfonic acid / water; ethylene glycol; ethyl acetate; acetone; toluene

2: dmap; triethylamine / dichloromethane; ethyl acetate

3: ammonium hydroxide; copper(I) iodide; triethylamine / tetrakis(triphenylphosphine)palladium ⁽⁰⁾ / methanol; hexane; ethyl acetate; N,N-dimethyl-formamide

With dmap; ammonium hydroxide; copper(I) iodide; toluene-4-sulfonic acid; triethylamine; tetrakis(triphenylphosphine)palladium ⁽⁰⁾; In methanol; hexane; dichloromethane; water; ethylene glycol; ethyl acetate; N,N-dimethyl-formamide; acetone; toluene;