(2S)-2-(4-{(1S)-1-[(tert-butoxycarbonyl)amino]ethyl}phenyl)-2-hydroxyethyl 4-methylbenzenesulfonate

Base Information

• Chemical Name: (2S)-2-(4-{(1S)-1-[(tert-butoxycarbonyl)amino]ethyl}phenyl)-2-hydroxyethyl 4-methylbenzenesulfonate
• CAS No.: 1037251-80-1
• Molecular Formula: C₂₂H₂₉NO₆S
• Molecular Weight: 435.541

Synonyms:(2S)-2-(4-{(1S)-1-[(tert-butoxycarbonyl)amino]ethyl}phenyl)-2-hydroxyethyl 4-methylbenzenesulfonate

Chemical Property of (2S)-2-(4-{(1S)-1-[(tert-butoxycarbonyl)amino]ethyl}phenyl)-2-hydroxyethyl 4-methylbenzenesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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Technology Process of (2S)-2-(4-{(1S)-1-[(tert-butoxycarbonyl)amino]ethyl}phenyl)-2-hydroxyethyl 4-methylbenzenesulfonate

There total 1 articles about (2S)-2-(4-{(1S)-1-[(tert-butoxycarbonyl)amino]ethyl}phenyl)-2-hydroxyethyl 4-methylbenzenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-butyl ((1S)-1-{4-[(1S)-1,2-dihydroxyethyl]phenyl}ethyl)carbamate (1037251-78-7) + p-toluenesulfonyl chloride (98-59-9) → (2S)-2-(4-{(1S)-1-[(tert-butoxycarbonyl)amino]ethyl}phenyl)-2-hydroxyethyl 4-methylbenzenesulfonate (1037251-80-1)

Guidance literature:

With pyridine; at 0 ℃;

Reference yield:

(2S)-2-(4-{(1S)-1-[(tert-butoxycarbonyl)amino]ethyl}phenyl)-2-hydroxyethyl 4-methylbenzenesulfonate (1037251-80-1) → tert-butyl ((1S)-1-{4-[(2S)-oxiran-2-yl]phenyl}ethyl)carbamate (1037251-82-3)

Guidance literature:

With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; In chloroform; water; at 20 ℃;

upstream raw materials:

tert-butyl ((1S)-1-{4-[(1S)-1,2-dihydroxyethyl]phenyl}ethyl)carbamate

p-toluenesulfonyl chloride

Downstream raw materials:

tert-butyl ((1S)-1-{4-[(2S)-oxiran-2-yl]phenyl}ethyl)carbamate

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