7-chlorobenzo[e][1,2,3]oxathiazine 2,2-dioxide

Base Information

• Chemical Name: 7-chlorobenzo[e][1,2,3]oxathiazine 2,2-dioxide
• CAS No.: 1449600-79-6
• Molecular Formula: C₇H₄ClNO₃S
• Molecular Weight: 217.633
• Mol file: 1449600-79-6.mol

Synonyms:7-chlorobenzo[e][1,2,3]oxathiazine 2,2-dioxide

Chemical Property of 7-chlorobenzo[e][1,2,3]oxathiazine 2,2-dioxide

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 7-chlorobenzo[e][1,2,3]oxathiazine 2,2-dioxide

There total 1 articles about 7-chlorobenzo[e][1,2,3]oxathiazine 2,2-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-chlorosalicylaldehyde (2420-26-0) → 7-chlorobenzo[e][1,2,3]oxathiazine 2,2-dioxide (1449600-79-6)

Guidance literature:

With sulphamoyl chloride; In N,N-dimethyl acetamide; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1021/ol402977w

Reference yield: 99.0%

7-chlorobenzo[e][1,2,3]oxathiazine 2,2-dioxide (1449600-79-6) + phenylboronic acid (98-80-6) → (R)-7-chloro-4-phenyl-3,4-dihydrobenzo[e][1,2,3]oxathiazine-2,2-dioxide

Guidance literature:

With nickel(II) perchlorate hexahydrate; (S)-2-(2'-(diphenylphosphino)biphenyl-2-yl)-4-isopropyl-4,5-dihydrooxazole; In 2,2,2-trifluoroethanol; at 60 ℃; for 48h;

DOI:10.1039/C6CC08759K

Reference yield: 95.0%

1-phenyl-1-cyclobutanol (935-64-8) + 7-chlorobenzo[e][1,2,3]oxathiazine 2,2-dioxide (1449600-79-6) → 4-(7-chloro-2,2-dioxidobenzo[e][1,2,3]oxathiazin-4-yl)-1-phenylbutan-1-one

Guidance literature:

With dipotassium peroxodisulfate; silver nitrate; In water; acetonitrile; at 60 ℃; for 48h; Schlenk technique;

DOI:10.1039/d0cc07181a

upstream raw materials:

4-chlorosalicylaldehyde