(S)-4'-(2-{N-benzyl-N-[3-(4-benzyloxyphenoxy)-2-hydroxypropyl]amino}ethyl)-2-(1-naphthyl)acetanilide

Base Information

Chemical Name:(S)-4'-(2-{N-benzyl-N-[3-(4-benzyloxyphenoxy)-2-hydroxypropyl]amino}ethyl)-2-(1-naphthyl)acetanilide
CAS No.:1160619-72-6
Molecular Formula:C₄₃H₄₂N₂O₄
Molecular Weight:650.817
Hs Code.:

Synonyms:(S)-4'-(2-{N-benzyl-N-[3-(4-benzyloxyphenoxy)-2-hydroxypropyl]amino}ethyl)-2-(1-naphthyl)acetanilide

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Chemical Property of (S)-4'-(2-{N-benzyl-N-[3-(4-benzyloxyphenoxy)-2-hydroxypropyl]amino}ethyl)-2-(1-naphthyl)acetanilide

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Technology Process of (S)-4'-(2-{N-benzyl-N-[3-(4-benzyloxyphenoxy)-2-hydroxypropyl]amino}ethyl)-2-(1-naphthyl)acetanilide

There total 1 articles about (S)-4'-(2-{N-benzyl-N-[3-(4-benzyloxyphenoxy)-2-hydroxypropyl]amino}ethyl)-2-(1-naphthyl)acetanilide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: 5121-00-6
naphthalen-1-yl-acetyl chloride

: 1160619-69-1
(S)-1-{N-[2-(4-aminophenyl)ethyl]-N-benzylamino}-3-(4-benzyloxyphenoxy)-2-propanol

: 1160619-72-6
(S)-4'-(2-{N-benzyl-N-[3-(4-benzyloxyphenoxy)-2-hydroxypropyl]amino}ethyl)-2-(1-naphthyl)acetanilide

Guidance literature:: With triethylamine; In chloroform; at 0 - 20 ℃;
DOI:10.1016/j.ejmech.2009.01.022

Reference yield: 43.0%

: 1160619-72-6
(S)-4'-(2-{N-benzyl-N-[3-(4-benzyloxyphenoxy)-2-hydroxypropyl]amino}ethyl)-2-(1-naphthyl)acetanilide

: (S)-4'-(2-{[2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino}ethyl)-2-(1-naphthyl)acetanilide hydrochloride

Guidance literature:: (S)-4'-(2-{N-benzyl-N-[3-(4-benzyloxyphenoxy)-2-hydroxypropyl]amino}ethyl)-2-(1-naphthyl)acetanilide; With palladium 10% on activated carbon; hydrogen; In ethanol; for 15h;

With hydrogenchloride; In methanol; ethyl acetate;
DOI:10.1016/j.ejmech.2009.01.022