Benzenepropanol, 2-bromo-beta,beta-dimethyl-

Base Information

Chemical Name:Benzenepropanol, 2-bromo-beta,beta-dimethyl-
CAS No.:149080-25-1
Molecular Formula:C₁₁H₁₅BrO
Molecular Weight:243.143
Hs Code.:
DSSTox Substance ID:DTXSID801294662

Synonyms:3-(2-bromophenyl)-2,2-dimethylpropan-1-ol;Benzenepropanol, 2-bromo-beta,beta-dimethyl-;149080-25-1;DTXSID801294662;AKOS015368662;2-Bromo-beta,beta-dimethylbenzenepropanol;F2147-6168

Suppliers and Price of Benzenepropanol, 2-bromo-beta,beta-dimethyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Benzenepropanol, 2-bromo-beta,beta-dimethyl-

Chemical Property:

XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:242.03063
Heavy Atom Count:13
Complexity:156

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(CC1=CC=CC=C1Br)CO

Technology Process of Benzenepropanol, 2-bromo-beta,beta-dimethyl-

There total 3 articles about Benzenepropanol, 2-bromo-beta,beta-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 149080-24-0
3-(2-bromophenyl)-2,2-dimethylpropanoic acid

: 149080-25-1
3-(2-bromophenyl)-2,2-dimethylpropanol

Guidance literature:: With dimethylsulfide borane complex; In tetrahydrofuran; at 0 - 20 ℃; for 22h;
DOI:10.1021/jm00062a013

Reference yield:

: 149080-23-9
3-(2-bromophenyl)-2,2-dimethylpropanoic acid methyl ester

: 149080-25-1
3-(2-bromophenyl)-2,2-dimethylpropanol

Guidance literature:: Multi-step reaction with 2 steps

1: 19.8 g / aq. NaOH / tetrahydrofuran / 18 h / 65 °C

2: 18.6 g / borane-dimethyl sulfide / tetrahydrofuran / 22 h / 0 - 20 °C

With sodium hydroxide; dimethylsulfide borane complex; In tetrahydrofuran;
DOI:10.1021/jm00062a013

Reference yield:

: 3433-80-5
1-Bromo-2-bromomethyl-benzene

: 149080-25-1
3-(2-bromophenyl)-2,2-dimethylpropanol

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) LDA, 2.) HMPA / 1.) THF, hexane, -78 deg C, 30 min, 2.) THF, hexane, a) -78 deg C, 1 h, b) 0 deg C, 18 h

2: 19.8 g / aq. NaOH / tetrahydrofuran / 18 h / 65 °C

3: 18.6 g / borane-dimethyl sulfide / tetrahydrofuran / 22 h / 0 - 20 °C

With N,N,N,N,N,N-hexamethylphosphoric triamide; sodium hydroxide; dimethylsulfide borane complex; lithium diisopropyl amide; In tetrahydrofuran;
DOI:10.1021/jm00062a013