N-(2-phenylethyl)hexanamide

Base Information

• Chemical Name: N-(2-phenylethyl)hexanamide
• CAS No.: 10264-26-3
• Molecular Formula: C₁₄H₂₁NO
• Molecular Weight: 219.327

Synonyms:N-(2-phenylethyl)hexanamide

Chemical Property of N-(2-phenylethyl)hexanamide

Chemical Property:

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Technology Process of N-(2-phenylethyl)hexanamide

There total 15 articles about N-(2-phenylethyl)hexanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

phenethylamine (64-04-0) + hexanoic acid (142-62-1) → N-(2-phenylethyl)hexanamide (10264-26-3)

Guidance literature:

With C₁₆H₂₀N₅O₂⁽¹⁺⁾*Cl^(1-); In dichloromethane; at 20 ℃; for 0.166667h;

DOI:10.1039/d1ob00450f

Reference yield: 95.0%

N-(4-chlorophenyl)-N-hexanoyl-4-nitrobenzenesulfonamide + phenethylamine (64-04-0) → N-(2-phenylethyl)hexanamide (10264-26-3) + N-(4-chlorophenyl)-4-nitrobenzenesulfonamide (16937-03-4)

Guidance literature:

With potassium carbonate; In water; at 80 ℃; for 0.0833333h; Green chemistry;

DOI:10.1515/znb-2015-0076

Reference yield: 93.0%

hexanoyltrimethylsilane (63578-18-7) + O-diethylcarbamoyl-N-phenethylhydroxylamine (1590361-11-7) → N-(2-phenylethyl)hexanamide (10264-26-3)

Guidance literature:

With citric acid; In water; acetonitrile; at 20 ℃; for 0.25h; chemoselective reaction;

DOI:10.1002/anie.202012459

upstream raw materials:

Hexanoyl chloride

phenethylamine

hexanoic acid hydrazide

hexanoic acid

Downstream raw materials:

C₁₄H₂₇NO

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