2-amino-6-bromo-4-(4-methylbenzoyl)pyridine-3,5-dicarbonitrile

Base Information

• Chemical Name: 2-amino-6-bromo-4-(4-methylbenzoyl)pyridine-3,5-dicarbonitrile
• CAS No.: 1350555-67-7
• Molecular Formula: C₁₅H₉BrN₄O
• Molecular Weight: 341.167
• Mol file: 1350555-67-7.mol

Synonyms:2-amino-6-bromo-4-(4-methylbenzoyl)pyridine-3,5-dicarbonitrile

Chemical Property of 2-amino-6-bromo-4-(4-methylbenzoyl)pyridine-3,5-dicarbonitrile

Chemical Property:

Purity/Quality:

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Technology Process of 2-amino-6-bromo-4-(4-methylbenzoyl)pyridine-3,5-dicarbonitrile

There total 2 articles about 2-amino-6-bromo-4-(4-methylbenzoyl)pyridine-3,5-dicarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

C15H8N4O*H3N → 2-amino-6-bromo-4-(4-methylbenzoyl)pyridine-3,5-dicarbonitrile (1350555-67-7)

Guidance literature:

With hydrogen bromide; In iso-butanol; at 70 - 75 ℃; for 0.166667h;

DOI:10.1134/S107042801110006X

Reference yield: 76.0%

potassium 2-(4′-methylbenzoyl)-1,1,3,3-tetracyanopropenide → 2-amino-6-bromo-4-(4-methylbenzoyl)pyridine-3,5-dicarbonitrile (1350555-67-7)

Guidance literature:

With hydrogen bromide; In isopropyl alcohol; at 85 ℃;

DOI:10.1007/s10593-017-2093-x

Reference yield: 75.0%

2-amino-6-bromo-4-(4-methylbenzoyl)pyridine-3,5-dicarbonitrile (1350555-67-7) → 4-amino-6-bromo-1-hydroxy-1-(4-methylphenyl)-3-oxo-2,3-dihydro-1H-pyrrolo[3,4-c]pyridine-7-carbonitrile

Guidance literature:

2-amino-6-bromo-4-(4-methylbenzoyl)pyridine-3,5-dicarbonitrile; With sulfuric acid; at 20 ℃;

With water; at 20 ℃;

DOI:10.1007/s10593-017-2093-x