Technology Process of C36H33N3O4S
There total 11 articles about C36H33N3O4S which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C35H33N3O4S; paraformaldehyde;
With
sodium disulfate;
In
tetrahydrofuran;
at 23 ℃;
for 5h;
With
caesium carbonate;
In
tetrahydrofuran;
for 3h;
DOI:10.1021/ol202475r
- Guidance literature:
-
C35H32BrN3O4S;
With
tert.-butyl lithium;
In
diethyl ether; pentane;
at -40 - 20 ℃;
for 1.5h;
Inert atmosphere;
paraformaldehyde;
In
diethyl ether; pentane;
at 20 ℃;
for 2.5h;
DOI:10.1021/ol202475r
- Guidance literature:
-
Multi-step reaction with 9 steps
1.1: toluene / Reflux
2.1: pyridinium perbromide hydrobromide / tetrahydrofuran; chloroform / 2.33 h / -10 °C
3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0 - 20 °C
3.2: 4 h / 0 - 20 °C
4.1: hydrazine hydrate / ethanol / Reflux
5.1: methanol / 24 h / 20 °C
6.1: boron trifluoride diethyl etherate / tetrahydrofuran; dichloromethane / 0.25 h / -40 °C / Inert atmosphere
6.2: 4 h / -40 - 20 °C
7.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 0 °C / Inert atmosphere
7.2: 0 °C
8.1: tert.-butyl lithium / diethyl ether; pentane / 1.5 h / -40 - 20 °C / Inert atmosphere
9.1: sodium disulfate / tetrahydrofuran / 5 h / 23 °C
9.2: 3 h
With
sodium disulfate; pyridinium perbromide hydrobromide; boron trifluoride diethyl etherate; tert.-butyl lithium; sodium hydride; hydrazine hydrate;
In
tetrahydrofuran; methanol; diethyl ether; ethanol; dichloromethane; chloroform; N,N-dimethyl-formamide; toluene; mineral oil; pentane;
DOI:10.1021/ol202475r
