(+)-(1R,2R)-3-[2-(dimethylamino)-methyl-1-hydroxycyclohexyl]phenol decanoate

Base Information

Chemical Name:(+)-(1R,2R)-3-[2-(dimethylamino)-methyl-1-hydroxycyclohexyl]phenol decanoate
CAS No.:1334208-77-3
Molecular Formula:C₁₀H₂₀O₂*C₁₅H₂₃NO₂
Molecular Weight:421.621
Hs Code.:

Synonyms:(+)-(1R,2R)-3-[2-(dimethylamino)-methyl-1-hydroxycyclohexyl]phenol decanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (+)-(1R,2R)-3-[2-(dimethylamino)-methyl-1-hydroxycyclohexyl]phenol decanoate

Chemical Property:

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Technology Process of (+)-(1R,2R)-3-[2-(dimethylamino)-methyl-1-hydroxycyclohexyl]phenol decanoate

There total 2 articles about (+)-(1R,2R)-3-[2-(dimethylamino)-methyl-1-hydroxycyclohexyl]phenol decanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.2%

: 334-48-5
1-decanoic acid

: 144830-14-8
(+)-O-Demethyltramadol

: 1334208-77-3
(+)-(1R,2R)-3-[2-(dimethylamino)-methyl-1-hydroxycyclohexyl]phenol decanoate

Guidance literature:: In pentane; at 20 - 30 ℃; for 24.5h; Product distribution / selectivity;

Reference yield:

: 148262-77-5,185453-02-5
(+)-O-Demethyltramadol hydrochloride

: 1334208-77-3
(+)-(1R,2R)-3-[2-(dimethylamino)-methyl-1-hydroxycyclohexyl]phenol decanoate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide / water / 0.65 h / 22 °C / pH 6 - 9.93

2: pentane / 24.5 h / 20 - 30 °C

With sodium hydroxide; In water; pentane;