5-bromo-1-[3-hydroxy-4-(hydroxymethyl)cyclopentyl]pyrimidine-2,4(1H,3H)-dione

Base Information

Chemical Name:5-bromo-1-[3-hydroxy-4-(hydroxymethyl)cyclopentyl]pyrimidine-2,4(1H,3H)-dione
CAS No.:83967-02-6
Molecular Formula:C₁₀H₁₃BrN₂O₄
Molecular Weight:305.128
Hs Code.:

Synonyms:2,4(1H,3H)-Pyrimidinedione,5-bromo-1-[3-hydroxy-4-(hydroxymethyl)cyclopentyl]-, (1a,3b,4a)- (9CI); 2,4(1H,3H)-Pyrimidinedione,5-bromo-1-[3-hydroxy-4-(hydroxymethyl)cyclopentyl]-, (1a,3b,4a)-(?à)-; (?à)-5-Bromo-1-[(1a,3b,4a)-3-hydroxy-4-(hydroxymethyl)cyclopentyl]-2,4(1H,3H)-pyrimidinedione;NSC 321823

Suppliers and Price of 5-bromo-1-[3-hydroxy-4-(hydroxymethyl)cyclopentyl]pyrimidine-2,4(1H,3H)-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of 5-bromo-1-[3-hydroxy-4-(hydroxymethyl)cyclopentyl]pyrimidine-2,4(1H,3H)-dione

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:1.793g/cm³

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-bromo-1-[3-hydroxy-4-(hydroxymethyl)cyclopentyl]pyrimidine-2,4(1H,3H)-dione

There total 3 articles about 5-bromo-1-[3-hydroxy-4-(hydroxymethyl)cyclopentyl]pyrimidine-2,4(1H,3H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.7%

: 83967-16-2
(+/-)-5-bromo-<(1α,3β,4α)-3-hydroxy-4-(hydroxymethyl)cyclopentyl>-2,4(1H,3H)-pyrimidinedione diacetate

: 83967-02-6
(+/-)-5-bromo-(1α,3β,4α)-1-<3-hydroxy-4-(hydroxymethyl)cyclopentyl>-2,4(1H,3H)-pyrimidinedione

Guidance literature:: With ammonia; In methanol; for 72h; Ambient temperature;
DOI:10.1021/jm00356a008

Reference yield:

: 62102-28-7
(+/-)-1-<(1β,3α,4β)-3-hydroxy-4-(hydroxymethyl)cyclopentyl>-2,4(1H,3H)-pyrimidinedione

: 83967-02-6
(+/-)-5-bromo-(1α,3β,4α)-1-<3-hydroxy-4-(hydroxymethyl)cyclopentyl>-2,4(1H,3H)-pyrimidinedione

Guidance literature:: Multi-step reaction with 3 steps

1: Heating

2: bromine / acetic acid / 3 h / Ambient temperature

3: 73.7 percent / NH₃ / methanol / 72 h / Ambient temperature

With ammonia; bromine; In methanol; acetic acid;
DOI:10.1021/jm00356a008

Reference yield:

: 95313-01-2
(+/-)-1-<(1α,3β,4α)-3-hydroxy-4-(hydroxymethyl)cyclopentyl>-2,4(1H,3H)-pyrimidinedione diacetate

: 83967-02-6
(+/-)-5-bromo-(1α,3β,4α)-1-<3-hydroxy-4-(hydroxymethyl)cyclopentyl>-2,4(1H,3H)-pyrimidinedione

Guidance literature:: Multi-step reaction with 2 steps

1: bromine / acetic acid / 3 h / Ambient temperature

2: 73.7 percent / NH₃ / methanol / 72 h / Ambient temperature

With ammonia; bromine; In methanol; acetic acid;
DOI:10.1021/jm00356a008