Threonylphenylalanine

Base Information

Chemical Name:Threonylphenylalanine
CAS No.:16875-27-7
Molecular Formula:C13H18 N2 O4
Molecular Weight:266.297
Hs Code.:2924299090
DSSTox Substance ID:DTXSID101346616
Nikkaji Number:J307.687C
Wikidata:Q27144972
Metabolomics Workbench ID:78989
ChEMBL ID:CHEMBL3321993
Mol file:16875-27-7.mol

Synonyms:H-Thr-Phe-OH;Thr-Phe;threonylphenylalanine;16875-27-7;L-THREONYL-L-PHENYLALANINE;CHEBI:74862;CHEMBL3321993;(S)-2-((2S,3R)-2-Amino-3-hydroxybutanamido)-3-phenylpropanoic acid;TF dipeptide;T-F Dipeptide;threonyl-phenylalanine;L-Thr-L-Phe;Threoninylphenylalanine;N-Threonylphenylalanine;Threoninyl-Phenylalanine;H-Thr-Phe-OH, AldrichCPR;L-Threoninyl-L-Phenylalanine;SCHEMBL233445;Threonine Phenylalanine dipeptide;Threonine-Phenylalanine dipeptide;DTXSID101346616;HY-P4626;BDBM50049727;MFCD00038591;CS-0655422;Q27144972;(2S)-2-[(2S,3R)-2-AMINO-3-HYDROXYBUTANAMIDO]-3-PHENYLPROPANOIC ACID

Suppliers and Price of Threonylphenylalanine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
H-THR-PHE-OH
200mg
$ 175.00

TRC
H-THR-PHE-OH
25mg
$ 45.00

American Custom Chemicals Corporation
THR-PHE-OH 98.00%
5G
$ 1790.25

Total 12 raw suppliers

Chemical Property of Threonylphenylalanine

Chemical Property:

Vapor Pressure:2.62E-14mmHg at 25°C
Refractive Index:1.579
Boiling Point:580.3°C at 760 mmHg
Flash Point:304.8°C
PSA：112.65000
Density:1.282g/cm³
LogP:0.59780
Storage Temp.:-15°C
XLogP3:-3.1
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:266.12665706
Heavy Atom Count:19
Complexity:316

Purity/Quality:

98%Min ^*data from raw suppliers

H-THR-PHE-OH ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(C(=O)NC(CC1=CC=CC=C1)C(=O)O)N)O
Isomeric SMILES:C[C@H]([C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)O)N)O

Technology Process of Threonylphenylalanine

There total 2 articles about Threonylphenylalanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 17896-50-3
N--O-<α,α,α-trifluor-1-benzyloxycarbonylamino-aethyl>-Thr-Phe

: 16875-27-7
H-Thr-Phe-OH

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; acetic acid;
DOI:10.1002/cber.19681010323

Reference yield:

: 17896-49-0
N--O-<α,α,α-trifluor-1-benzyloxycarbonylamino-aethyl>-Thr-Phe-methylester

: 16875-27-7
H-Thr-Phe-OH

Guidance literature:: Multi-step reaction with 2 steps

1: aq. NaOH / dioxane / Ambient temperature

2: H₂ / Pd-C / methanol; acetic acid

With sodium hydroxide; hydrogen; palladium on activated charcoal; In 1,4-dioxane; methanol; acetic acid;
DOI:10.1002/cber.19681010323

Reference yield:

: 1568912-20-8
H-Phe-Gly-OPh

: 16875-27-7
H-Thr-Phe-OH

: 1568912-61-7
H-Phe-Gly-Thr-Phe-OH

Guidance literature:: With benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; In aq. phosphate buffer; acetonitrile; at 40 ℃; pH=7.6;
DOI:10.2174/09298665113206660097