3-chloro-N-(diphenylphosphinoylmethyl)-N-methylisonicotinamide

Base Information Edit

Chemical Name:3-chloro-N-(diphenylphosphinoylmethyl)-N-methylisonicotinamide
CAS No.:380227-43-0
Molecular Formula:C₂₀H₁₈ClN₂O₂P
Molecular Weight:384.802
Hs Code.:
Mol file:380227-43-0.mol

Synonyms:3-chloro-N-(diphenylphosphinoylmethyl)-N-methylisonicotinamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-chloro-N-(diphenylphosphinoylmethyl)-N-methylisonicotinamide Edit

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Technology Process of 3-chloro-N-(diphenylphosphinoylmethyl)-N-methylisonicotinamide

There total 2 articles about 3-chloro-N-(diphenylphosphinoylmethyl)-N-methylisonicotinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 88912-27-0
3-chloro-isonicotinic acid

: 122365-23-5
N-[(diphenylphosphinoyl)methyl]-N-methylamine

: 380227-43-0
3-chloro-N-(diphenylphosphinoylmethyl)-N-methylisonicotinamide

Guidance literature:: 3-chloro-isonicotinic acid; With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 0 ℃; for 0.5h;

N-[(diphenylphosphinoyl)methyl]-N-methylamine; In dichloromethane; at 20 ℃; for 2h; Further stages.;
DOI:10.1021/jo0105944