2-BROMO-4,5-DIMETHOXYANILINE

Base Information

• Chemical Name: 2-BROMO-4,5-DIMETHOXYANILINE
• CAS No.: 16791-41-6
• Molecular Formula: C8H10 Br N O2
• Molecular Weight: 232.077
• Hs Code.: 2922299090
• Mol file: 16791-41-6.mol

Synonyms:Aniline,2-bromo-4,5-dimethoxy- (8CI); 2-Bromo-4,5-dimethoxyaniline

Chemical Property of 2-BROMO-4,5-DIMETHOXYANILINE

Chemical Property:

• Melting Point: 51 °C(Solv: methanol (67-56-1))
• Boiling Point: 297.7±35.0 °C(Predicted)
• PKA: 2.71±0.10(Predicted)
• PSA: 44.48000
• Density: 1.488±0.06 g/cm3(Predicted)
• LogP: 2.62970

Purity/Quality:

98%min ^*data from raw suppliers

2-Bromo-4,5-dimethoxyaniline 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-BROMO-4,5-DIMETHOXYANILINE

There total 7 articles about 2-BROMO-4,5-DIMETHOXYANILINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

3,4-dimethoxyaniline (6315-89-5) → 2-bromo-4,5-dimethoxyaniline (16791-41-6)

Guidance literature:

With tetra-N-butylammonium tribromide; In methanol; dichloromethane; for 20h; Ambient temperature;

DOI:10.1021/ja953080t

Reference yield: 42.0%

4-Bromoveratrole (2859-78-1) → 2-bromo-4,5-dimethoxyaniline (16791-41-6)

Guidance literature:

With O-(4-nitrobenzoyl)hydroxylammonium trifluoromethanesulfonate; iron(II) bromide; silver(I) triflimide; In 2,2,2-trifluoroethanol; water; at 30 ℃; for 2h;

DOI:10.1002/chem.201605476

Reference yield:

1-bromo-4,5-dimethoxy-2-nitro-benzene (51072-66-3) → 2-bromo-4,5-dimethoxyaniline (16791-41-6)

Guidance literature:

With hydrogen; In ethanol; at 69.84 ℃; for 8h; under 22502.3 Torr; Autoclave;

DOI:10.1016/j.apcata.2019.04.033

upstream raw materials:

N-(2-bromo-4,5-dimethoxyphenyl)acetamide

3,4-dimethoxyaniline

3',4'-dimethoxyacetanilide

2-acetamido-4,5-dimethoxybenzoic acid

Downstream raw materials:

2-bromo-4,5-dimethoxy-N-(2-morpholin-4-yl-ethyl)-aniline

(2-Bromo-4,5-dimethoxy-phenyl)-but-3-enyl-amine

1,2-dibromo-4,5-dimethoxybenzene

(2-Bromo-4,5-dimethoxy-phenyl)-but-3-enyl-methyl-amine