O-Octadecyl-1,2-acetone glycerin acetal

Base Information

• Chemical Name: O-Octadecyl-1,2-acetone glycerin acetal
• CAS No.: 16725-43-2
• Molecular Formula: C24H48 O3
• Molecular Weight: 384.643
• Hs Code.: 2932999099
• Mol file: 16725-43-2.mol

Synonyms:1,3-Dioxolane,2,2-dimethyl-1-[(octadecyloxy)methyl]- (7CI)

Chemical Property of O-Octadecyl-1,2-acetone glycerin acetal

Chemical Property:

• Melting Point: 32-33 °C
• Boiling Point: 210-215 °C(Press: 1 Torr)
• PSA: 27.69000
• Density: 0.886±0.06 g/cm3(Predicted)
• LogP: 7.41600

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of O-Octadecyl-1,2-acetone glycerin acetal

There total 7 articles about O-Octadecyl-1,2-acetone glycerin acetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

n-octadecyl p-toluenesulfonate (3386-32-1) + (R,S)-2,2-dimethyl-1,3-dioxolane-4-methanol (100-79-8,36543-79-0) → 4-(n-octadecyloxymethyl)-2,2-dimethyl-1,3-dioxolane (16725-43-2)

Guidance literature:

With sodium hydride; In tetrahydrofuran;

DOI:10.1016/S0957-4166(99)00397-3

Reference yield: 65.0%

1-octadecanol (112-92-5) + solketal tosylate (23737-51-1,7305-59-1) → 4-(n-octadecyloxymethyl)-2,2-dimethyl-1,3-dioxolane (16725-43-2)

Guidance literature:

1-octadecanol; With sodium hydride; In 1,2-dimethoxyethane; mineral oil; for 1h; Reflux;

solketal tosylate; In 1,2-dimethoxyethane; ethylene glycol; mineral oil; at 100 ℃; for 48h;

DOI:10.3390/md16040101

Reference yield:

1-Bromooctadecane (112-89-0) + (R,S)-2,2-dimethyl-1,3-dioxolane-4-methanol (100-79-8,36543-79-0) → 4-(n-octadecyloxymethyl)-2,2-dimethyl-1,3-dioxolane (16725-43-2)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; at 60 ℃; for 6h;

DOI:10.1021/jm00105a058

upstream raw materials:

n-iodooctadecane

(R,S)-2,2-dimethyl-1,3-dioxolane-4-methanol

1-octadecyl methanesulfonate

n-octadecyl p-toluenesulfonate

Downstream raw materials:

2-methoxy-3-octadecyloxy-1-propanol

1-O-octadecyl-2-O-methyl-3-O-trityl-rac-glycerol

2-hydroxy-3-(octadecyloxy)propyl 2-(trimethylammonio)ethyl phosphate

2-(benzyloxy)-3-(octadecyloxy)-1-propanol

Refernces

• 1、 Gupta,Kummerow. "-". . p. 409. Retrieved 1959.
• 2、 Pinault, Michelle,Guimaraes, Cyrille,Couthon, Hélène,Thibonnet, Jér?me,Fontaine, Delphine,Chant?me, Aurélie,Chevalier, Stephan,Besson, Pierre,Jaffrès, Paul-Alain,Vandier, Christophe. "Synthesis of alkyl-glycerolipids standards for gas chromatography analysis: Application for chimera and shark liver oils". . . Retrieved 2018/04/16.