1,3,3-TRIMETHYLINDOLINO-6'-BROMOBENZOPYRYLOSPIRAN

Base Information

• Chemical Name: 1,3,3-TRIMETHYLINDOLINO-6'-BROMOBENZOPYRYLOSPIRAN
• CAS No.: 16650-14-9
• Molecular Formula: C19H18 Br N O
• Molecular Weight: 356.26
• Hs Code.: 2934999090
• Mol file: 16650-14-9.mol

Synonyms:Spiro[2H-1-benzopyran-2,2'-indoline],6-bromo-1',3',3'-trimethyl- (8CI); 6-Bromo-1',3',3'-trimethylspiro[2H-1-benzopyran-2,2'-indoline]

Chemical Property of 1,3,3-TRIMETHYLINDOLINO-6'-BROMOBENZOPYRYLOSPIRAN

Chemical Property:

• Vapor Pressure: 2.55E-08mmHg at 25°C
• Refractive Index: 1.68
• Boiling Point: 450.8°C at 760 mmHg
• Flash Point: 226.5°C
• PSA: 12.47000
• Density: 1.44g/cm³
• LogP: 5.04360

Purity/Quality:

98%,99%, ^*data from raw suppliers

1,3,3-Trimethylindolino-6'-bromobenzopyrylospiran [Photochromic Compound] ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,3,3-TRIMETHYLINDOLINO-6'-BROMOBENZOPYRYLOSPIRAN

There total 10 articles about 1,3,3-TRIMETHYLINDOLINO-6'-BROMOBENZOPYRYLOSPIRAN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

1,2,3,3-tetramethyl-3H-indolium iodide (5418-63-3) + 5-bromosalicyclaldehyde (1761-61-1) → 6-bromo-1',3',3'-trimethylspiro(2H-1-benzopyran-2,2'-indoline) (16650-14-9)

Guidance literature:

With cholin hydroxide; In water; at 80 ℃; for 1h; Green chemistry;

DOI:10.1080/00397911.2017.1395053

Reference yield: 70.0%

1,3,3-Trimethyl-2-methyleneindoline (118-12-7) + 5-bromosalicyclaldehyde (1761-61-1) → 6-bromo-1',3',3'-trimethylspiro(2H-1-benzopyran-2,2'-indoline) (16650-14-9)

Guidance literature:

In ethanol; Heating;

DOI:10.1002/mrc.1260301119

Reference yield: 37.0%

1,3,3-Trimethyl-2-methyleneindoline (118-12-7) + 5-bromosalicyclaldehyde (1761-61-1) → 6-bromo-1',3',3'-trimethylspiro(2H-1-benzopyran-2,2'-indoline) (16650-14-9) + C31H33BrN2O

Guidance literature:

In ethanol; for 0.216667h; Irradiation;

DOI:10.1080/00397919508010795

upstream raw materials:

1,3,3-Trimethyl-2-methyleneindoline

5-bromosalicyclaldehyde

1,2,3,3-tetramethyl-3H-indolium iodide