(-)-(1R,2R,3S)-2-(tert-butyldimethylsilyloxy)-3-((tert-butyldiphenylsilyloxy)methyl)-3-vinylcyclobutanol

Base Information

• Chemical Name: (-)-(1R,2R,3S)-2-(tert-butyldimethylsilyloxy)-3-((tert-butyldiphenylsilyloxy)methyl)-3-vinylcyclobutanol
• CAS No.: 1033126-56-5
• Molecular Formula: C₂₉H₄₄O₃Si₂
• Molecular Weight: 496.838
• Mol file: 1033126-56-5.mol

Synonyms:(-)-(1R,2R,3S)-2-(tert-butyldimethylsilyloxy)-3-((tert-butyldiphenylsilyloxy)methyl)-3-vinylcyclobutanol

Chemical Property of (-)-(1R,2R,3S)-2-(tert-butyldimethylsilyloxy)-3-((tert-butyldiphenylsilyloxy)methyl)-3-vinylcyclobutanol

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of (-)-(1R,2R,3S)-2-(tert-butyldimethylsilyloxy)-3-((tert-butyldiphenylsilyloxy)methyl)-3-vinylcyclobutanol

There total 1 articles about (-)-(1R,2R,3S)-2-(tert-butyldimethylsilyloxy)-3-((tert-butyldiphenylsilyloxy)methyl)-3-vinylcyclobutanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

tert-butyl(((1S,2R,3R)-2-(tert-butyldimethylsilyloxy)-3-(4-methoxybenzyloxy)-1-vinylcyclobutyl)methoxy)diphenylsilane (1033126-54-3) → (-)-(1R,2R,3S)-2-(tert-butyldimethylsilyloxy)-3-((tert-butyldiphenylsilyloxy)methyl)-3-vinylcyclobutanol (1033126-56-5)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 0.333333h;

DOI:10.1021/jo8004233

Reference yield: 93.0%

(-)-(1R,2R,3S)-2-(tert-butyldimethylsilyloxy)-3-((tert-butyldiphenylsilyloxy)methyl)-3-vinylcyclobutanol (1033126-56-5) → (+)-(2R,3S)-2-(tert-butyldimethylsilyloxy)-3-((tert-butyldiphenylsilyloxy)methyl)-3-vinylcyclobutanone (1033126-57-6)

Guidance literature:

With 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In dimethyl sulfoxide; at 20 ℃; for 4h;

DOI:10.1021/jo8004233

upstream raw materials:

tert-butyl(((1S,2R,3R)-2-(tert-butyldimethylsilyloxy)-3-(4-methoxybenzyloxy)-1-vinylcyclobutyl)methoxy)diphenylsilane

Downstream raw materials:

(+)-(2R,3S)-2-(tert-butyldimethylsilyloxy)-3-((tert-butyldiphenylsilyloxy)methyl)-3-vinylcyclobutanone