(2S)-2-{[(2R)-2-(6-amino-pyridin-3-yl)-2-hydroxy-ethylamino]-methyl}-chroman-6-sulfonic acid {4-[4-(3-cyclopentyl-propyl)-5-oxo-4,5-dihydro-tetrazol-1-yl]-phenyl}-amide

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Chemical Name:(2S)-2-{[(2R)-2-(6-amino-pyridin-3-yl)-2-hydroxy-ethylamino]-methyl}-chroman-6-sulfonic acid {4-[4-(3-cyclopentyl-propyl)-5-oxo-4,5-dihydro-tetrazol-1-yl]-phenyl}-amide
CAS No.:228710-19-8
Molecular Formula:C₃₂H₄₀N₈O₅S
Molecular Weight:648.786
Hs Code.:

(2S)-2-{[(2R)-2-(6-amino-pyridin-3-yl)-2-hydroxy-ethylamino]-methyl}-chroman-6-sulfonic acid {4-[4-(3-cyclopentyl-propyl)-5-oxo-4,5-dihydro-tetrazol-1-yl]-phenyl}-amide

Synonyms:(2S)-2-{[(2R)-2-(6-amino-pyridin-3-yl)-2-hydroxy-ethylamino]-methyl}-chroman-6-sulfonic acid {4-[4-(3-cyclopentyl-propyl)-5-oxo-4,5-dihydro-tetrazol-1-yl]-phenyl}-amide

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Chemical Property of (2S)-2-{[(2R)-2-(6-amino-pyridin-3-yl)-2-hydroxy-ethylamino]-methyl}-chroman-6-sulfonic acid {4-[4-(3-cyclopentyl-propyl)-5-oxo-4,5-dihydro-tetrazol-1-yl]-phenyl}-amide

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Technology Process of (2S)-2-{[(2R)-2-(6-amino-pyridin-3-yl)-2-hydroxy-ethylamino]-methyl}-chroman-6-sulfonic acid {4-[4-(3-cyclopentyl-propyl)-5-oxo-4,5-dihydro-tetrazol-1-yl]-phenyl}-amide

There total 1 articles about (2S)-2-{[(2R)-2-(6-amino-pyridin-3-yl)-2-hydroxy-ethylamino]-methyl}-chroman-6-sulfonic acid {4-[4-(3-cyclopentyl-propyl)-5-oxo-4,5-dihydro-tetrazol-1-yl]-phenyl}-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 228710-22-3
6-{4-[-(3-cyclopentyl-propyl)-5-oxo-4,5-dihydro-tetrazol-1-yl]-phenylsulfamoyl}-chroman-(2S)-2-carboxylic acid {2-[6-(2,5-dimethyl-pyrrol-1-yl)-pyridin-3-yl]-(2R)-2-hydroxy-ethylamino}-amide

: 228710-19-8
(2S)-2-{[(2R)-2-(6-amino-pyridin-3-yl)-2-hydroxy-ethylamino]-methyl}-chroman-6-sulfonic acid {4-[4-(3-cyclopentyl-propyl)-5-oxo-4,5-dihydro-tetrazol-1-yl]-phenyl}-amide

Guidance literature:: 6-{4-[-(3-cyclopentyl-propyl)-5-oxo-4,5-dihydro-tetrazol-1-yl]-phenylsulfamoyl}-chroman-(2S)-2-carboxylic acid {2-[6-(2,5-dimethyl-pyrrol-1-yl)-pyridin-3-yl]-(2R)-2-hydroxy-ethylamino}-amide; With ethanol; hydroxylamine hydrochloride; water; for 12h; Heating / reflux;

With sodium hydroxide; water; In ethanol; ethyl acetate; pH=10;