N-<(S)-3-tosyloxybutyl>-(R)-α-methoxy-α-(trifluoromethyl)phenylacetamide

Base Information

Chemical Name:N-<(S)-3-tosyloxybutyl>-(R)-α-methoxy-α-(trifluoromethyl)phenylacetamide
CAS No.:242462-22-2
Molecular Formula:C₂₁H₂₄F₃NO₅S
Molecular Weight:459.486
Hs Code.:

Synonyms:N-<(S)-3-tosyloxybutyl>-(R)-α-methoxy-α-(trifluoromethyl)phenylacetamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-<(S)-3-tosyloxybutyl>-(R)-α-methoxy-α-(trifluoromethyl)phenylacetamide

Chemical Property:

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Technology Process of N-<(S)-3-tosyloxybutyl>-(R)-α-methoxy-α-(trifluoromethyl)phenylacetamide

There total 3 articles about N-<(S)-3-tosyloxybutyl>-(R)-α-methoxy-α-(trifluoromethyl)phenylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 39637-99-5,20445-33-4
(S)-(+)-2-methoxy-2-trifluoromethyl-2-phenylacetyl chloride

: 242462-22-2
N-<(S)-3-tosyloxybutyl>-(R)-α-methoxy-α-(trifluoromethyl)phenylacetamide

Guidance literature:: Multi-step reaction with 2 steps

2: 70 mg / DMAP / pyridine / 48 h / Ambient temperature

With dmap; In pyridine;
DOI:10.1021/jo981901h

Reference yield:

: 98-59-9
p-toluenesulfonyl chloride

: (R)-3,3,3-Trifluoro-N-((S)-3-hydroxy-butyl)-2-methoxy-2-phenyl-propionamide

: 242462-22-2
N-<(S)-3-tosyloxybutyl>-(R)-α-methoxy-α-(trifluoromethyl)phenylacetamide

Guidance literature:: With dmap; In pyridine; for 48h; Ambient temperature;
DOI:10.1021/jo981901h

Reference yield:

: 242462-17-5
1-<(R)-α-methoxy-α-(trifluoromethyl)phenylacetyl>-(R)-2-methylazetidine

: 2-<(R)-α-methoxy-α-(trifluoromethyl)benzyl>-(R)-6-methyl-5,6-dihydro-4H-1,3-oxazole

: (S)-6-Methyl-2-((R)-2,2,2-trifluoro-1-methoxy-1-phenyl-ethyl)-5,6-dihydro-4H-[1,3]oxazine

: 242462-22-2
N-<(S)-3-tosyloxybutyl>-(R)-α-methoxy-α-(trifluoromethyl)phenylacetamide

Guidance literature:: With toluene-4-sulfonic acid; In benzene; at 70 ℃; for 1h; Product distribution; other reaction time;
DOI:10.1021/jo981901h