tert-butyl ({5-[(6-chloropyridin-3-yl)sulfonyl]-4-(2-fluorophenyl)-1,3-thiazol-2-yl}methyl)methylcarbamate

Base Information

Chemical Name:tert-butyl ({5-[(6-chloropyridin-3-yl)sulfonyl]-4-(2-fluorophenyl)-1,3-thiazol-2-yl}methyl)methylcarbamate
CAS No.:1138035-77-4
Molecular Formula:C₂₁H₂₁ClFN₃O₄S₂
Molecular Weight:497.999
Hs Code.:

Synonyms:tert-butyl ({5-[(6-chloropyridin-3-yl)sulfonyl]-4-(2-fluorophenyl)-1,3-thiazol-2-yl}methyl)methylcarbamate

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Chemical Property of tert-butyl ({5-[(6-chloropyridin-3-yl)sulfonyl]-4-(2-fluorophenyl)-1,3-thiazol-2-yl}methyl)methylcarbamate

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Technology Process of tert-butyl ({5-[(6-chloropyridin-3-yl)sulfonyl]-4-(2-fluorophenyl)-1,3-thiazol-2-yl}methyl)methylcarbamate

There total 1 articles about tert-butyl ({5-[(6-chloropyridin-3-yl)sulfonyl]-4-(2-fluorophenyl)-1,3-thiazol-2-yl}methyl)methylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 1138035-57-0
tert-butyl ({5-[(6-chloropyridin-3-yl)thio]-4-(2-fluorophenyl)-1,3-thiazol-2-yl}methyl)methylcarbamate

: 1138035-77-4
tert-butyl ({5-[(6-chloropyridin-3-yl)sulfonyl]-4-(2-fluorophenyl)-1,3-thiazol-2-yl}methyl)methylcarbamate

Guidance literature:: tert-butyl ({5-[(6-chloropyridin-3-yl)thio]-4-(2-fluorophenyl)-1,3-thiazol-2-yl}methyl)methylcarbamate; With acetic acid; 3-chloro-benzenecarboperoxoic acid; at 20 ℃; for 14h;

With sodium hydrogencarbonate; In water;

Reference yield: 49.0%

: 1138035-77-4
tert-butyl ({5-[(6-chloropyridin-3-yl)sulfonyl]-4-(2-fluorophenyl)-1,3-thiazol-2-yl}methyl)methylcarbamate

: 1138042-08-6
1-{5-[(6-chloropyridin-3-yl)sulfonyl]-4-(2-fluorophenyl)-1,3-thiazol-2-yl}-N-methylmethanamine hydrochloride

Guidance literature:: With hydrogenchloride; In ethanol; ethyl acetate; at 20 ℃; for 3h;

Reference yield: 34.0%

: 1138035-77-4
tert-butyl ({5-[(6-chloropyridin-3-yl)sulfonyl]-4-(2-fluorophenyl)-1,3-thiazol-2-yl}methyl)methylcarbamate

: 1138035-79-6
tert-butyl {[4-(2-fluorophenyl)-5-(pyridin-3-ylsulfonyl)-1,3-thiazol-2-yl]methyl}methylcarbamate

Guidance literature:: tert-butyl ({5-[(6-chloropyridin-3-yl)sulfonyl]-4-(2-fluorophenyl)-1,3-thiazol-2-yl}methyl)methylcarbamate; With hydrogen; palladium 10% on activated carbon; In tetrahydrofuran; ethanol; at 20 ℃; for 2h;

With sodium hydrogencarbonate; In water;