tetrahydro-2H-thiopyran-3-ol 1,1-dioxide

Base Information

• Chemical Name: tetrahydro-2H-thiopyran-3-ol 1,1-dioxide
• CAS No.: 94158-05-1
• Molecular Formula: C5H10 O3 S
• Molecular Weight: 150.199
• Hs Code.: 2934999090
• Mol file: 94158-05-1.mol

Synonyms:tetrahydro-2H-thiopyran-3-ol 1,1-dioxide

Chemical Property of tetrahydro-2H-thiopyran-3-ol 1,1-dioxide

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 378.1°Cat760mmHg
• Flash Point: 182.5°C
• PSA: 62.75000
• Density: 1.365g/cm³
• LogP: 0.63670

Purity/Quality:

97% ^*data from raw suppliers

3-hydroxy-1lambda6-thiane-1,1-dione ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of tetrahydro-2H-thiopyran-3-ol 1,1-dioxide

There total 5 articles about tetrahydro-2H-thiopyran-3-ol 1,1-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

tetrahydrothiopyran-3-one-1,1-dioxide (29431-37-6) → 3-hydroxytetrahydro-2H-thiopyran-1,1-dioxide (94158-05-1)

Guidance literature:

With sodium tetrahydroborate; In methanol; at 20 ℃; for 3h; Cooling with ice;

DOI:10.1080/00397911.2018.1486427

Reference yield: 63.0%

3-Hydroxytetrahydrothiopyran (22072-19-1) → 3-hydroxytetrahydro-2H-thiopyran-1,1-dioxide (94158-05-1)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In chloroform; for 2h; Ambient temperature;

DOI:10.1021/jo00355a018

Reference yield: 43.0%

4-pentene-1-thiosulfonic acid sodium salt → 3-hydroxytetrahydro-2H-thiopyran-1,1-dioxide (94158-05-1) + sodium pent-4-ene-1-sulfonate

Guidance literature:

With hydrogenchloride; oxygen; In methanol; at 20 ℃; for 96h;

DOI:10.1016/S0040-4020(02)00654-3

upstream raw materials:

tetrahydrothiopyran-3-one-1,1-dioxide

3-Hydroxytetrahydrothiopyran

pent-4-ene-1-sulfonyl chloride

dihydro-2H-thiopyran-3(4H)-one

Downstream raw materials:

tetrahydrothiopyran-3-one-1,1-dioxide

3,6-dihydro-2H-thiopyran 1,1-dioxide

3,4-dihydro-2H-thiopyran 1,1-dioxide

Ethyl 3,4,5,6,10-hexahydro-8-methyl-10-(3-nitrophenyl)-1,1-dioxo-2H-thiacycloocteno<3,2-b>pyridine-9-carboxylate