5-Chloro-1-methyl-1H-benzo[d]imidazol-2(3H)-one

Base Information

Chemical Name:5-Chloro-1-methyl-1H-benzo[d]imidazol-2(3H)-one
CAS No.:15965-71-6
Molecular Formula:C8H7 Cl N2 O
Molecular Weight:182.609
Hs Code.:
European Community (EC) Number:895-608-3
Mol file:15965-71-6.mol

Synonyms:15965-71-6;5-Chloro-1-methyl-1H-benzo[d]imidazol-2(3H)-one;6-chloro-3-methyl-1H-benzimidazol-2-one;2H-Benzimidazol-2-one,5-chloro-1,3-dihydro-1-methyl-(9CI);SCHEMBL3066593;2H-Benzimidazol-2-one, 5-chloro-1,3-dihydro-1-methyl-;ZABAVTWKCRNJIG-UHFFFAOYSA-N;AKOS027399366;EN300-3455048;5-chloro-1-methyl-1,3-dihydro-benzoimidazol-2-one;Z1509147664;5-Chloro-1-methyl-1,3-dihydro-2H-benzo[d]imidazol-2-one;5-chloro-1-methyl-2,3-dihydro-1H-1,3-benzodiazol-2-one

Suppliers and Price of 5-Chloro-1-methyl-1H-benzo[d]imidazol-2(3H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
5-chloro-1,3-dihydro-1-methyl-2H-Benzimidazol-2-one 97.00%
25G
$ 13000.00

AccelPharmtech
5-chloro-1,3-dihydro-1-methyl-2H-Benzimidazol-2-one 97.00%
5G
$ 6840.00

Total 5 raw suppliers

Chemical Property of 5-Chloro-1-methyl-1H-benzo[d]imidazol-2(3H)-one

Chemical Property:

PSA：37.79000
LogP:1.52000
XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:182.0246905
Heavy Atom Count:12
Complexity:209

Purity/Quality:

95% ^*data from raw suppliers

5-chloro-1,3-dihydro-1-methyl-2H-Benzimidazol-2-one 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C2=C(C=C(C=C2)Cl)NC1=O

Technology Process of 5-Chloro-1-methyl-1H-benzo[d]imidazol-2(3H)-one

There total 12 articles about 5-Chloro-1-methyl-1H-benzo[d]imidazol-2(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 5-chloro-3-methoxy-1-methyl-1,3-dihydro-2H-benzo[d]-imidazol-2-one

: 15965-71-6
5-chloro-1,3-dihydro-1-methyl-2H-benzimidazol-2-one

Guidance literature:: With samarium diiodide; In tetrahydrofuran; water monomer; at 0 ℃; for 3h;
DOI:10.1021/acs.joc.1c02929

Reference yield: 87.0%

: 117290-55-8
6-chloro-1,3-dihydro-3-methyl-1-(1-phenylethen-1yl)-2H-benzimidazol-2-one

: 15965-71-6
5-chloro-1,3-dihydro-1-methyl-2H-benzimidazol-2-one

Guidance literature:: With sulfuric acid; water; 1. 135 degC 25 min.; 2. 90 degC, 4 h;
DOI:10.1002/jhet.5570250151

Reference yield:

: N-methoxy-1-methyl-1-(4-chlorophenyl)urea

: 15965-71-6
5-chloro-1,3-dihydro-1-methyl-2H-benzimidazol-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 1-tert-butyl-4-iodobenzene; 3-chloro-benzenecarboperoxoic acid / 2,2,2-trifluoroethanol / 12 h / 20 °C

2: samarium diiodide / tetrahydrofuran; water monomer / 3 h / 0 °C

With samarium diiodide; 1-tert-butyl-4-iodobenzene; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; 2,2,2-trifluoroethanol; water monomer;
DOI:10.1021/acs.joc.1c02929