ETHYL-3-METHYL-2-HEXENOATE

Base Information

• Chemical Name: ETHYL-3-METHYL-2-HEXENOATE
• CAS No.: 15677-00-6
• Molecular Formula: C9H16 O2
• Molecular Weight: 156.22
• Hs Code.: 2916190090
• Mol file: 15677-00-6.mol

Synonyms:Ethyl3-methyl-2-hexenoate

Chemical Property of ETHYL-3-METHYL-2-HEXENOATE

Chemical Property:

• Boiling Point: 56-63 °C(Press: 1-2 Torr)
• PSA: 26.30000
• Density: 0.897±0.06 g/cm3(Predicted)
• LogP: 2.29590

Purity/Quality:

98% ^*data from raw suppliers

Ethyl-3-methyl-2-hexenoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ETHYL-3-METHYL-2-HEXENOATE

There total 6 articles about ETHYL-3-METHYL-2-HEXENOATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

2-Pentanone (107-87-9) + ethyl (triphenylphosphoranylidene)acetate (1099-45-2) → ethyl 3-methylhex-2-enoate (15677-00-6)

Guidance literature:

In xylene; at 50 ℃; for 30h; under 6750540 Torr;

DOI:10.1016/S0040-4039(00)96078-7

Reference yield: 67.0%

diethoxyphosphoryl-acetic acid ethyl ester (867-13-0) + 2-Pentanone (107-87-9) → ethyl 3-methylhex-2-enoate (15677-00-6)

Guidance literature:

With potassium tert-butylate; In benzene; at 20 ℃; for 10 - 12h;

DOI:10.1134/S107042800808006X

Reference yield:

Ethyl 3-hydroxy-3-methylhexanoate (24420-88-0) → ethyl 3-methylhex-2-enoate (15677-00-6)

Guidance literature:

With trichlorophosphate; benzene;

upstream raw materials:

Ethyl 3-hydroxy-3-methylhexanoate

2-Pentanone

ethyl 2-sulfanylacetate

ethyl (triphenylphosphoranylidene)acetate

Downstream raw materials:

3-methyl-2-hexenoic acid

(E)-3-methyl-1-phenylhept-2-en-1-one

3-methylhex-2-en-1-ol

Refernces

• 1、 Wu, Jie,Mu, Ran,Sun, Mingna,Zhao, Nan,Pan, Miaomiao,Li, Hongshuang,Dong, Yi,Sun, Zhaogang,Bai, Jie,Hu, Minwan,Nathan, Carl F.,Javid, Babak,Liu, Gang. "Derivatives of Natural Product Agrimophol as Disruptors of Intrabacterial pH Homeostasis in Mycobacterium tuberculosis". . p. 1087 - 1104. Retrieved 2019/05/22.
• 2、 Mirzabekova,Kuz'mina,Lukashov,Sokolova,Golosov,Kazakov,Perlova,Potapova,Kheinman,Ivanova. "Synthesis and biological activity of permethrinic acid analogs containing various substituents in position 2 of the cyclopropane ring". experimental part. p. 1139 - 1149. Retrieved 2009/09/25.