O-(1-{(4R,5R)-2,2-dimethyl-5-[(E)-pent-2-en-1-yl]-1,3-dioxolan-4-yl}-3-{(4R,5S)-5-[(4-methoxyphenoxy)methyl]-2-oxo-1,3-dioxolan-4-yl}prop-2-yn-1-yl) O-phenyl carbothioate

Base Information

Chemical Name:O-(1-{(4R,5R)-2,2-dimethyl-5-[(E)-pent-2-en-1-yl]-1,3-dioxolan-4-yl}-3-{(4R,5S)-5-[(4-methoxyphenoxy)methyl]-2-oxo-1,3-dioxolan-4-yl}prop-2-yn-1-yl) O-phenyl carbothioate
CAS No.:1439510-75-4
Molecular Formula:C₃₁H₃₄O₉S
Molecular Weight:582.672
Hs Code.:

O-(1-{(4R,5R)-2,2-dimethyl-5-[(E)-pent-2-en-1-yl]-1,3-dioxolan-4-yl}-3-{(4R,5S)-5-[(4-methoxyphenoxy)methyl]-2-oxo-1,3-dioxolan-4-yl}prop-2-yn-1-yl) O-phenyl carbothioate

Synonyms:O-(1-{(4R,5R)-2,2-dimethyl-5-[(E)-pent-2-en-1-yl]-1,3-dioxolan-4-yl}-3-{(4R,5S)-5-[(4-methoxyphenoxy)methyl]-2-oxo-1,3-dioxolan-4-yl}prop-2-yn-1-yl) O-phenyl carbothioate

Suppliers and Price of O-(1-{(4R,5R)-2,2-dimethyl-5-[(E)-pent-2-en-1-yl]-1,3-dioxolan-4-yl}-3-{(4R,5S)-5-[(4-methoxyphenoxy)methyl]-2-oxo-1,3-dioxolan-4-yl}prop-2-yn-1-yl) O-phenyl carbothioate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of O-(1-{(4R,5R)-2,2-dimethyl-5-[(E)-pent-2-en-1-yl]-1,3-dioxolan-4-yl}-3-{(4R,5S)-5-[(4-methoxyphenoxy)methyl]-2-oxo-1,3-dioxolan-4-yl}prop-2-yn-1-yl) O-phenyl carbothioate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of O-(1-{(4R,5R)-2,2-dimethyl-5-[(E)-pent-2-en-1-yl]-1,3-dioxolan-4-yl}-3-{(4R,5S)-5-[(4-methoxyphenoxy)methyl]-2-oxo-1,3-dioxolan-4-yl}prop-2-yn-1-yl) O-phenyl carbothioate

There total 12 articles about O-(1-{(4R,5R)-2,2-dimethyl-5-[(E)-pent-2-en-1-yl]-1,3-dioxolan-4-yl}-3-{(4R,5S)-5-[(4-methoxyphenoxy)methyl]-2-oxo-1,3-dioxolan-4-yl}prop-2-yn-1-yl) O-phenyl carbothioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₄H₃₀O₈

: 1005-56-7
phenylcarbonochloridothioate

: 1439510-75-4
O-(1-{(4R,5R)-2,2-dimethyl-5-[(E)-pent-2-en-1-yl]-1,3-dioxolan-4-yl}-3-{(4R,5S)-5-[(4-methoxyphenoxy)methyl]-2-oxo-1,3-dioxolan-4-yl}prop-2-yn-1-yl) O-phenyl carbothioate

Guidance literature:: With dmap; In acetonitrile; at 0 ℃; for 0.166667h; Inert atmosphere;
DOI:10.1021/ol401231y

Reference yield:

: 1439510-53-8
(4R,5S)-4-ethynyl-5-[(4-methoxyphenoxy)methyl]-2,2-dimethyl-1,3-dioxolane

: 1439510-75-4
O-(1-{(4R,5R)-2,2-dimethyl-5-[(E)-pent-2-en-1-yl]-1,3-dioxolan-4-yl}-3-{(4R,5S)-5-[(4-methoxyphenoxy)methyl]-2-oxo-1,3-dioxolan-4-yl}prop-2-yn-1-yl) O-phenyl carbothioate

Guidance literature:: Multi-step reaction with 5 steps

1: toluene-4-sulfonic acid / methanol / 17 h / 20 °C / Inert atmosphere

2: pyridine / dichloromethane / 0.5 h / 0 °C / Inert atmosphere

3: N-iodo-succinimide; silver nitrate / acetone / 0.25 h / 20 °C / Inert atmosphere

4: chromium dichloride; nickel dichloride / tetrahydrofuran / 1.17 h / 0 - 20 °C / Inert atmosphere

5: dmap / acetonitrile / 0.17 h / 0 °C / Inert atmosphere

With pyridine; chromium dichloride; dmap; N-iodo-succinimide; toluene-4-sulfonic acid; silver nitrate; nickel dichloride; In tetrahydrofuran; methanol; dichloromethane; acetone; acetonitrile; 4: |Nozaki-Hiyama-Kishi Reaction;
DOI:10.1021/ol401231y

Reference yield:

: 1439510-39-0
{(4S,5R)-2,2-dimethyl-5-[(E)-pent-2-en-1-yl]-1,3-dioxolan-4-yl}methanol

: 1439510-75-4
O-(1-{(4R,5R)-2,2-dimethyl-5-[(E)-pent-2-en-1-yl]-1,3-dioxolan-4-yl}-3-{(4R,5S)-5-[(4-methoxyphenoxy)methyl]-2-oxo-1,3-dioxolan-4-yl}prop-2-yn-1-yl) O-phenyl carbothioate

Guidance literature:: Multi-step reaction with 3 steps

1: Dess-Martin periodane; sodium hydrogencarbonate / dichloromethane / 0.25 h / 20 °C / Inert atmosphere

2: chromium dichloride; nickel dichloride / tetrahydrofuran / 1.17 h / 0 - 20 °C / Inert atmosphere

3: dmap / acetonitrile / 0.17 h / 0 °C / Inert atmosphere

With chromium dichloride; dmap; sodium hydrogencarbonate; Dess-Martin periodane; nickel dichloride; In tetrahydrofuran; dichloromethane; acetonitrile; 1: |Dess-Martin Oxidation / 2: |Nozaki-Hiyama-Kishi Reaction;
DOI:10.1021/ol401231y