adamantane-1-carboxylic acid 3-(4-{2-[2-(2-{4-[5-(4-amino-phenyl)-cyclohepta-1,3,6-trienyl]-phenoxy}-ethoxy)-ethoxy]-ethoxy}-phenyl)-propyl ester

Base Information

• Chemical Name: adamantane-1-carboxylic acid 3-(4-{2-[2-(2-{4-[5-(4-amino-phenyl)-cyclohepta-1,3,6-trienyl]-phenoxy}-ethoxy)-ethoxy]-ethoxy}-phenyl)-propyl ester
• CAS No.: 764687-75-4
• Molecular Formula: C₄₅H₅₃NO₆
• Molecular Weight: 703.919
• Mol file: 764687-75-4.mol

Synonyms:adamantane-1-carboxylic acid 3-(4-{2-[2-(2-{4-[5-(4-amino-phenyl)-cyclohepta-1,3,6-trienyl]-phenoxy}-ethoxy)-ethoxy]-ethoxy}-phenyl)-propyl ester

Chemical Property of adamantane-1-carboxylic acid 3-(4-{2-[2-(2-{4-[5-(4-amino-phenyl)-cyclohepta-1,3,6-trienyl]-phenoxy}-ethoxy)-ethoxy]-ethoxy}-phenyl)-propyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of adamantane-1-carboxylic acid 3-(4-{2-[2-(2-{4-[5-(4-amino-phenyl)-cyclohepta-1,3,6-trienyl]-phenoxy}-ethoxy)-ethoxy]-ethoxy}-phenyl)-propyl ester

There total 7 articles about adamantane-1-carboxylic acid 3-(4-{2-[2-(2-{4-[5-(4-amino-phenyl)-cyclohepta-1,3,6-trienyl]-phenoxy}-ethoxy)-ethoxy]-ethoxy}-phenyl)-propyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

C39H47O6(1+)*BF4(1-) + aniline (62-53-3) → adamantane-1-carboxylic acid 3-(4-{2-[2-(2-{4-[3-(4-amino-phenyl)-cyclohepta-1,4,6-trienyl]-phenoxy}-ethoxy)-ethoxy]-ethoxy}-phenyl)-propyl ester + adamantane-1-carboxylic acid 3-(4-{2-[2-(2-{4-[5-(4-amino-phenyl)-cyclohepta-1,3,6-trienyl]-phenoxy}-ethoxy)-ethoxy]-ethoxy}-phenyl)-propyl ester (764687-75-4)

Guidance literature:

In dichloromethane; at 20 ℃; for 5h;

DOI:10.1002/chem.200400243

Reference yield:

triethylene glycol di-(p-toluenesulfonate) (19249-03-7) → adamantane-1-carboxylic acid 3-(4-{2-[2-(2-{4-[5-(4-amino-phenyl)-cyclohepta-1,3,6-trienyl]-phenoxy}-ethoxy)-ethoxy]-ethoxy}-phenyl)-propyl ester (764687-75-4)

Guidance literature:

Multi-step reaction with 4 steps

1.1: NaOEt / acetonitrile / 0.5 h / 20 °C

1.2: 50 percent / acetonitrile / 6 h / Heating

2.1: 91 percent / pyridine / 4 h / 75 °C

3.1: (Ph)3C(+)*BF₄(-) / CH₂Cl₂

4.1: 25 percent / CH₂Cl₂ / 5 h / 20 °C

With pyridine; sodium ethanolate; trityl tetrafluoroborate; In dichloromethane; acetonitrile;

DOI:10.1002/chem.200400243

Reference yield:

3-(4-hydroxyphenyl)propan-1-ol (10210-17-0) → adamantane-1-carboxylic acid 3-(4-{2-[2-(2-{4-[5-(4-amino-phenyl)-cyclohepta-1,3,6-trienyl]-phenoxy}-ethoxy)-ethoxy]-ethoxy}-phenyl)-propyl ester (764687-75-4)

Guidance literature:

Multi-step reaction with 4 steps

1.1: NaOEt / acetonitrile / 0.5 h / 20 °C

1.2: 50 percent / acetonitrile / 6 h / Heating

2.1: 91 percent / pyridine / 4 h / 75 °C

3.1: (Ph)3C(+)*BF₄(-) / CH₂Cl₂

4.1: 25 percent / CH₂Cl₂ / 5 h / 20 °C

With pyridine; sodium ethanolate; trityl tetrafluoroborate; In dichloromethane; acetonitrile;

DOI:10.1002/chem.200400243

upstream raw materials:

aniline

3-(4-hydroxyphenyl)propan-1-ol

7-(4-hydroxyphenyl)-1,3,5-cycloheptatriene

1-Adamantanecarbonyl chloride