(E)-3-((2R,4S,5R)-4-((tert-butyldiphenylsilyl)-oxy)-5-vinyltetrahydrofuran-2-yl)allyl acetate

Base Information

Chemical Name:(E)-3-((2R,4S,5R)-4-((tert-butyldiphenylsilyl)-oxy)-5-vinyltetrahydrofuran-2-yl)allyl acetate
CAS No.:1434154-29-6
Molecular Formula:C₂₇H₃₄O₄Si
Molecular Weight:450.65
Hs Code.:

Synonyms:(E)-3-((2R,4S,5R)-4-((tert-butyldiphenylsilyl)-oxy)-5-vinyltetrahydrofuran-2-yl)allyl acetate

Suppliers and Price of (E)-3-((2R,4S,5R)-4-((tert-butyldiphenylsilyl)-oxy)-5-vinyltetrahydrofuran-2-yl)allyl acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (E)-3-((2R,4S,5R)-4-((tert-butyldiphenylsilyl)-oxy)-5-vinyltetrahydrofuran-2-yl)allyl acetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (E)-3-((2R,4S,5R)-4-((tert-butyldiphenylsilyl)-oxy)-5-vinyltetrahydrofuran-2-yl)allyl acetate

There total 1 articles about (E)-3-((2R,4S,5R)-4-((tert-butyldiphenylsilyl)-oxy)-5-vinyltetrahydrofuran-2-yl)allyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: (E)-3-(4-hydroxy-5-vinyltetrahydrofuran-2-yl)allyl acetate

: 58479-61-1
tert-butylchlorodiphenylsilane

: 1434154-29-6
(E)-3-((2R,4S,5R)-4-((tert-butyldiphenylsilyl)-oxy)-5-vinyltetrahydrofuran-2-yl)allyl acetate

: 1434154-58-1
(E)-3-((2R,4S,5S)-4-((tert-butyldiphenylsilyl)-oxy)-5-vinyltetrahydrofuran-2-yl)allyl acetate

Guidance literature:: With 1H-imidazole; In dichloromethane; at 20 ℃; for 6h; Inert atmosphere;
DOI:10.1021/jo4004647

Reference yield: 94.0%

: 1434154-29-6
(E)-3-((2R,4S,5R)-4-((tert-butyldiphenylsilyl)-oxy)-5-vinyltetrahydrofuran-2-yl)allyl acetate

: 1434154-59-2
C₂₅H₃₂O₃Si

Guidance literature:: With potassium carbonate; In methanol; at 20 ℃; for 20h;
DOI:10.1021/jo4004647

Reference yield:

: 1434154-29-6
(E)-3-((2R,4S,5R)-4-((tert-butyldiphenylsilyl)-oxy)-5-vinyltetrahydrofuran-2-yl)allyl acetate

: C₄₆H₆₄O₅Si₃

Guidance literature:: Multi-step reaction with 6 steps

1.1: potassium carbonate / methanol / 20 h / 20 °C

2.1: titanium(IV) isopropylate; diethyl (2S,3S)-tartrate; tert.-butylhydroperoxide / dichloromethane; decane / 0.33 h / 20 °C / Inert atmosphere; Molecular sieve

2.2: -20 °C / Inert atmosphere

3.1: sodium bis(2-methoxyethoxy)aluminium dihydride / tetrahydrofuran / 1 h / -30 - 0 °C / Inert atmosphere

4.1: 1H-imidazole / dichloromethane / 20 °C / Inert atmosphere

5.1: 1H-imidazole / 20 °C

6.1: ozone; oxygen / dichloromethane; methanol / -78 °C

6.2: 1 h / -78 - 20 °C

With 1H-imidazole; titanium(IV) isopropylate; tert.-butylhydroperoxide; diethyl (2S,3S)-tartrate; oxygen; potassium carbonate; ozone; sodium bis(2-methoxyethoxy)aluminium dihydride; In tetrahydrofuran; methanol; decane; dichloromethane; 2.1: |Sharpless Asymmetric Epoxidation;
DOI:10.1021/jo4004647