methyl 2-(tert-butoxycarbonylamino)-2-(3-(2',4'-difluorobiphenyl-4-ylsulfonamido)phenyl)propanoate

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Chemical Name:methyl 2-(tert-butoxycarbonylamino)-2-(3-(2',4'-difluorobiphenyl-4-ylsulfonamido)phenyl)propanoate
CAS No.:1218932-53-6
Molecular Formula:C₂₇H₂₈F₂N₂O₆S
Molecular Weight:546.592
Hs Code.:

Synonyms:methyl 2-(tert-butoxycarbonylamino)-2-(3-(2',4'-difluorobiphenyl-4-ylsulfonamido)phenyl)propanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of methyl 2-(tert-butoxycarbonylamino)-2-(3-(2',4'-difluorobiphenyl-4-ylsulfonamido)phenyl)propanoate

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Technology Process of methyl 2-(tert-butoxycarbonylamino)-2-(3-(2',4'-difluorobiphenyl-4-ylsulfonamido)phenyl)propanoate

There total 1 articles about methyl 2-(tert-butoxycarbonylamino)-2-(3-(2',4'-difluorobiphenyl-4-ylsulfonamido)phenyl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 942475-01-6
2′,4′-difluoro-biphenyl-4-sulfonylchloride

: 1218932-52-5
methyl 2-(3-aminophenyl)-2-(tert-butoxycarbonylamino)propanoate

: 1218932-53-6
methyl 2-(tert-butoxycarbonylamino)-2-(3-(2',4'-difluorobiphenyl-4-ylsulfonamido)phenyl)propanoate

Guidance literature:: With pyridine; In dichloromethane; at 0 - 20 ℃; for 3h;

Reference yield: 44.0%

: 1218932-53-6
methyl 2-(tert-butoxycarbonylamino)-2-(3-(2',4'-difluorobiphenyl-4-ylsulfonamido)phenyl)propanoate

: 1218932-54-7
tert-butyl 2-(3-(2',4'-difluorobiphenyl-4-ylsulfonamido)phenyl)-1-hydroxypropan-2-ylcarbamate

Guidance literature:: methyl 2-(tert-butoxycarbonylamino)-2-(3-(2',4'-difluorobiphenyl-4-ylsulfonamido)phenyl)propanoate; With lithium aluminium tetrahydride; In tetrahydrofuran; at -5 - 20 ℃;

With water; ammonium chloride; In tetrahydrofuran; at -5 ℃;