benzyl 2-carbobenzyloxyamino-2-deoxy-α-D-galactopyranosiduronic acid

Base Information

• Chemical Name: benzyl 2-carbobenzyloxyamino-2-deoxy-α-D-galactopyranosiduronic acid
• CAS No.: 114612-09-8
• Molecular Formula: C₂₁H₂₃NO₈
• Molecular Weight: 417.416
• Mol file: 114612-09-8.mol

Synonyms:benzyl 2-carbobenzyloxyamino-2-deoxy-α-D-galactopyranosiduronic acid

Chemical Property of benzyl 2-carbobenzyloxyamino-2-deoxy-α-D-galactopyranosiduronic acid

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of benzyl 2-carbobenzyloxyamino-2-deoxy-α-D-galactopyranosiduronic acid

There total 6 articles about benzyl 2-carbobenzyloxyamino-2-deoxy-α-D-galactopyranosiduronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

benzyl 2-carbobenzyloxyamino-2-deoxy-α-D-galactopyranoside (4713-66-0) → benzyl 2-carbobenzyloxyamino-2-deoxy-α-D-galactopyranosiduronic acid (114612-09-8)

Guidance literature:

With oxygen; sodium hydrogencarbonate; platinum; In water; at 80 ℃; for 5h;

DOI:10.7164/antibiotics.55.191

Reference yield:

2-carbobenzyloxyamino-2-deoxy-D-galactopyranose (3006-58-4) → benzyl 2-carbobenzyloxyamino-2-deoxy-α-D-galactopyranosiduronic acid (114612-09-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 71 percent / acetyl chloride / 1.5 h / 80 °C

2: 97 percent / O₂; NaHCO₃ / Pt / H₂O / 5 h / 80 °C

With oxygen; sodium hydrogencarbonate; acetyl chloride; platinum; In water;

DOI:10.7164/antibiotics.55.191

Reference yield:

benzyl chloroformate (501-53-1,94274-21-2) → benzyl 2-carbobenzyloxyamino-2-deoxy-α-D-galactopyranosiduronic acid (114612-09-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 78 percent / NaHCO₃ / H₂O / 18 h / 20 °C

2: 71 percent / acetyl chloride / 1.5 h / 80 °C

3: 97 percent / O₂; NaHCO₃ / Pt / H₂O / 5 h / 80 °C

With oxygen; sodium hydrogencarbonate; acetyl chloride; platinum; In water;

DOI:10.7164/antibiotics.55.191

upstream raw materials:

benzyl 2-carbobenzyloxyamino-2-deoxy-α-D-galactopyranoside

2-carbobenzyloxyamino-2-deoxy-D-galactopyranose

D-(+)-galactosamine hydrochloride

benzyl chloroformate

Downstream raw materials:

(R)-2-[((2S,3R,4R,5R,6S)-6-Benzyloxy-5-benzyloxycarbonylamino-3,4-dihydroxy-tetrahydro-pyran-2-carbonyl)-amino]-3-phenyl-propionic acid methyl ester

N-(benzyl 2-carbobenzyloxyamino-2-deoxy-α-D-galactopyranosiduronyl)-β-D-phenylalanine methyl ester

N-(benzyl 2-carbobenzyloxyamino-2-deoxy-α-D-galactopyranosiduronyl)glycine ethyl ester

(S)-3-[((2S,3R,4R,5R,6S)-6-Benzyloxy-5-benzyloxycarbonylamino-3,4-dihydroxy-tetrahydro-pyran-2-carbonyl)-amino]-3-p-tolyl-propionic acid ethyl ester