2,5-Dinitropyridine

Base Information

• Chemical Name: 2,5-Dinitropyridine
• CAS No.: 15009-92-4
• Molecular Formula: C5H3N3O4
• Molecular Weight: 169.1
• Hs Code.: 2933399090
• DSSTox Substance ID: DTXSID40376514
• Wikidata: Q82165416
• Mol file: 15009-92-4.mol

Synonyms:2,5-dinitropyridine;15009-92-4;Pyridine, 2,5-dinitro-;2,5-DIMITROPYRIDINE;SCHEMBL10936934;DTXSID40376514;AKOS006292123;FT-0645838;A809005

Chemical Property of 2,5-Dinitropyridine

Chemical Property:

• Vapor Pressure: 7.98E-05mmHg at 25°C
• Refractive Index: 1.621
• Boiling Point: 352.1 °C at 760 mmHg
• Flash Point: 166.7 °C
• PSA: 104.53000
• Density: 1.59 g/cm³
• LogP: 1.94440
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 0
• Exact Mass: 169.01235559
• Heavy Atom Count: 12
• Complexity: 196

Purity/Quality:

97% ^*data from raw suppliers

2,5-Dinitropyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC(=NC=C1[N+](=O)[O-])[N+](=O)[O-]

Technology Process of 2,5-Dinitropyridine

There total 2 articles about 2,5-Dinitropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

2-dimethylsulfylimino-5-nitropyridine (134251-84-6) → 2,5-dinitropyridine (15009-92-4)

Guidance literature:

With dihydrogen peroxide; trifluoroacetic acid; In dichloromethane; at 0 ℃;

DOI:10.1007/BF00476986

Reference yield:

5-nitro-pyridin-2-ylamine (4214-76-0,67476-67-9) → 2,5-dinitropyridine (15009-92-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 42 percent / N-chlorosuccinimide / CH₂Cl₂ / 3 h / -20 °C

2: 79 percent / trifluoroacetic acid, H₂O₂ / CH₂Cl₂ / 0 °C

With N-chloro-succinimide; dihydrogen peroxide; trifluoroacetic acid; In dichloromethane;

DOI:10.1007/BF00476986

Reference yield: 95.0%

2,5-dinitropyridine (15009-92-4) + N-acetyl-p-phenylenediamine (122-80-5) → N-[4-(5-nitropyridin-2-ylamino)phenyl]acetamide (801243-60-7)

Guidance literature:

In ethanol; acetic acid; at 20 ℃; for 2h;

DOI:10.1007/s10593-008-0013-9

upstream raw materials:

2-dimethylsulfylimino-5-nitropyridine

5-nitro-pyridin-2-ylamine

Downstream raw materials:

C₂₃H₁₈N₃O₂P

N-[4-(5-nitropyridin-2-ylamino)phenyl]acetamide