1-[2-(1,3-Dioxolan-2-yl)phenyl]imidazole

Base Information

Chemical Name:1-[2-(1,3-Dioxolan-2-yl)phenyl]imidazole
CAS No.:151055-84-4
Molecular Formula:C₁₂H₁₂N₂O₂
Molecular Weight:216.239
Hs Code.:
DSSTox Substance ID:DTXSID801258939

Synonyms:151055-84-4;DTXSID801258939;1-[2-(1,3-Dioxolan-2-yl)phenyl]-1H-imidazole

Suppliers and Price of 1-[2-(1,3-Dioxolan-2-yl)phenyl]imidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 1-[2-(1,3-Dioxolan-2-yl)phenyl]imidazole

Chemical Property:

XLogP3:1.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:216.089877630
Heavy Atom Count:16
Complexity:231

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COC(O1)C2=CC=CC=C2N3C=CN=C3

Technology Process of 1-[2-(1,3-Dioxolan-2-yl)phenyl]imidazole

There total 1 articles about 1-[2-(1,3-Dioxolan-2-yl)phenyl]imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6630-33-7
ortho-bromobenzaldehyde

: 151055-84-4
2-<2-(1H-imidazol-1-yl)phenyl>-1,3-dioxolane

Guidance literature:: Multi-step reaction with 2 steps

1.1: toluene-4-sulfonic acid / benzene / 6 h / 20 °C / Reflux

2.1: sodium hydride / mineral oil; N,N-dimethyl-formamide / 20 °C

2.2: 4 h / 150 °C

With sodium hydride; toluene-4-sulfonic acid; In N,N-dimethyl-formamide; mineral oil; benzene;
DOI:10.1002/ejoc.201301507

Reference yield: 100.0%

: 151055-84-4
2-<2-(1H-imidazol-1-yl)phenyl>-1,3-dioxolane

: 151055-86-6
2-(1H-imidazol-1-yl)benzaldehyde

Guidance literature:: With hydrogenchloride; In water; at 20 ℃; for 2h;
DOI:10.1002/ejoc.201301507

Reference yield:

: 151055-84-4
2-<2-(1H-imidazol-1-yl)phenyl>-1,3-dioxolane

: 1,4-dihydro-2,6-dimethyl-4-[2-(1H-imidazol-1-yl)phenyl]-3,5-pyridinedicarboxylic acid, diethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 93 percent / 1 N aq. HCl / 2 h / Ambient temperature

2: 18 percent / 30percent aq. NH₄OH / ethanol / 6 h / Heating

With hydrogenchloride; ammonium hydroxide; In ethanol;
DOI:10.1021/jm00072a017