(-)-TROGER'S BASE

Base Information Edit

Chemical Name:(-)-TROGER'S BASE
CAS No.:14645-24-0
Molecular Formula:C17H18 N2
Molecular Weight:250.34
Hs Code.:
Mol file:14645-24-0.mol

Synonyms:6H,12H-5,11-Methanodibenzo[b,f][1,5]diazocine,2,8-dimethyl-, (5R)-; 6H,12H-5,11-Methanodibenzo[b,f][1,5]diazocine,2,8-dimethyl-, (5R,11R)-(-)- (8CI); (-)-Troeger's base; (-)-Troger's base;(5R,11R)-(-)-2,8-Dimethyl-6H,12H-5,11-methanodibenzo[b,f][1,5]diazocine;Troeger's base

Suppliers and Price of (-)-TROGER'S BASE

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
(?)-Trger’s base for chiral derivatization, ≥99.0%
100mg
$ 128.00

Sigma-Aldrich
Troger’s Base 98%
5 g
$ 32.60

Total 6 raw suppliers

Chemical Property of (-)-TROGER'S BASE Edit

Chemical Property:

Vapor Pressure:1.11E-08mmHg at 25°C
Melting Point:127-131 °C
Refractive Index:1.685
Boiling Point:461°Cat760mmHg
PKA:4.53±0.20(Predicted)
Flash Point:213.5°C
PSA：6.48000
Density:1.21g/cm³
LogP:3.73110

Purity/Quality:

98%,99%, ^*data from raw suppliers

(?)-Trger’s base for chiral derivatization, ≥99.0% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn,N,Xi
Statements: 22-50/53-36/37/38
Safety Statements: 26-60-61

MSDS Files:

Useful:

Uses It was used as an standard analyte for testing the enantioseparation capability of the chiral stationary phase column; in a study to understand the covalently bonded cellulose tris(3,5-dimethylphenylcarbamate) on a silica monolithic capillary column.

Technology Process of (-)-TROGER'S BASE

There total 13 articles about (-)-TROGER'S BASE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 900804-66-2,900804-67-3
(-)-R,R-2,8-dimethyl-6,12-dihydro-5,11-methanodibenzo-[b,f ][1,5]diazocine*(-)-O,O′-dibenzoyl-L-tartaric acid

: 21451-74-1,14645-24-0,529-81-7
Troeger's base

Guidance literature:: With sodium carbonate; In dichloromethane; water;
DOI:10.1021/jo401873x

Reference yield: 88.0%

: 1619230-61-3,1619230-62-4
(S_S,S_S,5R,11R)-2,8-dimethyl-4,10-bis(p-tolylsulfinyl)-6,12-dihydro-5,11-methanodibenzo[b,f][1,5]diazocine

: 21451-74-1,14645-24-0,529-81-7
Troeger's base

Guidance literature:: (S_S,S_S,5R,11R)-2,8-dimethyl-4,10-bis(p-tolylsulfinyl)-6,12-dihydro-5,11-methanodibenzo[b,f][1,5]diazocine; With n-butyllithium; iodobenzene; In tetrahydrofuran; diethyl ether; hexane; at -78 ℃; for 0.166667h; Schlenk technique; Inert atmosphere;

With water; In tetrahydrofuran; diethyl ether; hexane; at -78 - 20 ℃; Schlenk technique; Inert atmosphere;
DOI:10.1039/c4cc03963g