[3-[acetyl(phenylmethoxy)amino]propyl]-phosphonic acid bis[1-(hexadecanoyloxy)ethyl] ester

Base Information

Chemical Name:[3-[acetyl(phenylmethoxy)amino]propyl]-phosphonic acid bis[1-(hexadecanoyloxy)ethyl] ester
CAS No.:865622-25-9
Molecular Formula:C₄₈H₈₆NO₉P
Molecular Weight:852.186
Hs Code.:

Synonyms:[3-[acetyl(phenylmethoxy)amino]propyl]-phosphonic acid bis[1-(hexadecanoyloxy)ethyl] ester

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Chemical Property of [3-[acetyl(phenylmethoxy)amino]propyl]-phosphonic acid bis[1-(hexadecanoyloxy)ethyl] ester

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Technology Process of [3-[acetyl(phenylmethoxy)amino]propyl]-phosphonic acid bis[1-(hexadecanoyloxy)ethyl] ester

There total 3 articles about [3-[acetyl(phenylmethoxy)amino]propyl]-phosphonic acid bis[1-(hexadecanoyloxy)ethyl] ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

: 65657-61-6
1-chloroethyl palmitate

: 581106-29-8
[3-[acetyl(phenylmethoxy)amino]propyl]phosphonic acid

: 865622-25-9
[3-[acetyl(phenylmethoxy)amino]propyl]-phosphonic acid bis[1-(hexadecanoyloxy)ethyl] ester

Guidance literature:: With triethylamine; sodium iodide; In various solvent(s); at 60 ℃; for 6h;
DOI:10.1002/ardp.200500976

Reference yield:

: 557090-55-8
O-(benzylhydroxylamino)propylphosphonic acid diethyl ester

: 865622-25-9
[3-[acetyl(phenylmethoxy)amino]propyl]-phosphonic acid bis[1-(hexadecanoyloxy)ethyl] ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: 83 percent / Et₃N / CH₂Cl₂ / 20 °C

2.1: bromotrimethylsilane / 20 °C

2.2: 83 percent / water / 20 °C

3.1: 35 percent / Et₃N; NaI / various solvent(s) / 6 h / 60 °C

With trimethylsilyl bromide; triethylamine; sodium iodide; In dichloromethane;
DOI:10.1002/ardp.200500976

Reference yield:

: 581106-28-7
[3-[acetyl(phenylmethoxy)amino]propyl]phosphonic acid diethyl ester

: 865622-25-9
[3-[acetyl(phenylmethoxy)amino]propyl]-phosphonic acid bis[1-(hexadecanoyloxy)ethyl] ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: bromotrimethylsilane / 20 °C

1.2: 83 percent / water / 20 °C

2.1: 35 percent / Et₃N; NaI / various solvent(s) / 6 h / 60 °C

With trimethylsilyl bromide; triethylamine; sodium iodide; In various solvent(s);
DOI:10.1002/ardp.200500976