N-{2-[(RS)-2-(tert-butyldimethylsilyl)-1,1-dioxo-1,2-thiazetidin-3-yl]acetyl}-L-alanyl-L-proline benzyl ester

Base Information

Chemical Name:N-{2-[(RS)-2-(tert-butyldimethylsilyl)-1,1-dioxo-1,2-thiazetidin-3-yl]acetyl}-L-alanyl-L-proline benzyl ester
CAS No.:840525-49-7
Molecular Formula:C₂₅H₃₉N₃O₆SSi
Molecular Weight:537.753
Hs Code.:

Synonyms:N-{2-[(RS)-2-(tert-butyldimethylsilyl)-1,1-dioxo-1,2-thiazetidin-3-yl]acetyl}-L-alanyl-L-proline benzyl ester

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Chemical Property of N-{2-[(RS)-2-(tert-butyldimethylsilyl)-1,1-dioxo-1,2-thiazetidin-3-yl]acetyl}-L-alanyl-L-proline benzyl ester

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Technology Process of N-{2-[(RS)-2-(tert-butyldimethylsilyl)-1,1-dioxo-1,2-thiazetidin-3-yl]acetyl}-L-alanyl-L-proline benzyl ester

There total 1 articles about N-{2-[(RS)-2-(tert-butyldimethylsilyl)-1,1-dioxo-1,2-thiazetidin-3-yl]acetyl}-L-alanyl-L-proline benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 156977-60-5
<2-(tert-butyldimethylsilyl)-1,2-thiazetidin-3-yl>acetic acid 1,1-dioxide

: Boc-Ala-Pro-OBn hydrochloride

: 840525-49-7
N-{2-[(RS)-2-(tert-butyldimethylsilyl)-1,1-dioxo-1,2-thiazetidin-3-yl]acetyl}-L-alanyl-L-proline benzyl ester

Guidance literature:: Boc-Ala-Pro-OBn hydrochloride; With triethylamine; In dichloromethane; for 0.0833333h;

<2-(tert-butyldimethylsilyl)-1,2-thiazetidin-3-yl>acetic acid 1,1-dioxide; With 1-hydroxy-pyrrolidine-2,5-dione; dicyclohexyl-carbodiimide; In dichloromethane; at -5 ℃; for 20h;