Technology Process of C13H18F3N3O4SSi
There total 5 articles about C13H18F3N3O4SSi which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C19H33F3O5SSi2;
With
methanesulfonyl chloride; triethylamine;
at 0 ℃;
for 0.5h;
Inert atmosphere;
With
sodium azide; 15-crown-5;
In
N,N-dimethyl-formamide;
at 70 ℃;
for 12h;
Inert atmosphere;
With
hydrogenchloride;
In
methanol; N,N-dimethyl-formamide;
at 20 ℃;
for 12h;
Inert atmosphere;
DOI:10.1073/pnas.1015265108
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: diethyl ether / 0.08 h / 0 °C / Inert atmosphere
2.1: 2,6-dimethylpyridine / dichloromethane / 0.33 h / 20 °C / Inert atmosphere
2.2: 0.17 h / -78 °C / Inert atmosphere
2.3: 1 h / 20 °C / Inert atmosphere
3.1: methanesulfonyl chloride; triethylamine / 0.5 h / 0 °C / Inert atmosphere
3.2: 12 h / 70 °C / Inert atmosphere
3.3: 12 h / 20 °C / Inert atmosphere
With
2,6-dimethylpyridine; methanesulfonyl chloride; triethylamine;
In
diethyl ether; dichloromethane;
DOI:10.1073/pnas.1015265108
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 2,6-dimethylpyridine / dichloromethane / 0.33 h / 20 °C / Inert atmosphere
1.2: 0.17 h / -78 °C / Inert atmosphere
1.3: 1 h / 20 °C / Inert atmosphere
2.1: methanesulfonyl chloride; triethylamine / 0.5 h / 0 °C / Inert atmosphere
2.2: 12 h / 70 °C / Inert atmosphere
2.3: 12 h / 20 °C / Inert atmosphere
With
2,6-dimethylpyridine; methanesulfonyl chloride; triethylamine;
In
dichloromethane;
DOI:10.1073/pnas.1015265108
