5-(2,4-difluorophenyl)-4,5-diazatricyclo[5.2.1.0(2,6)]deca-2⁽⁶⁾,3-dien-3-yl-phenylmethanone

Base Information

• Chemical Name: 5-(2,4-difluorophenyl)-4,5-diazatricyclo[5.2.1.0(2,6)]deca-2⁽⁶⁾,3-dien-3-yl-phenylmethanone
• CAS No.: 1024003-60-8
• Molecular Formula: C₂₁H₁₆F₂N₂O
• Molecular Weight: 350.368

Synonyms:5-(2,4-difluorophenyl)-4,5-diazatricyclo[5.2.1.0(2,6)]deca-2⁽⁶⁾,3-dien-3-yl-phenylmethanone

Chemical Property of 5-(2,4-difluorophenyl)-4,5-diazatricyclo[5.2.1.0(2,6)]deca-2⁽⁶⁾,3-dien-3-yl-phenylmethanone

Chemical Property:

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Technology Process of 5-(2,4-difluorophenyl)-4,5-diazatricyclo[5.2.1.0(2,6)]deca-2⁽⁶⁾,3-dien-3-yl-phenylmethanone

There total 1 articles about 5-(2,4-difluorophenyl)-4,5-diazatricyclo[5.2.1.0(2,6)]deca-2⁽⁶⁾,3-dien-3-yl-phenylmethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

bromobenzene (108-86-1,52753-63-6) + N5-methoxy-N5-methyl-(2,4-difluorophenyl)-3,4-diazatricyclo[5.2.1.0(2,6)]deca-2(6),4-dien-5-carboxamide (1024005-10-4) → 5-(2,4-difluorophenyl)-4,5-diazatricyclo[5.2.1.0(2,6)]deca-2(6),3-dien-3-yl-phenylmethanone (1024003-60-8)

Guidance literature:

With magnesium; In diethyl ether; at 20 - 35 ℃; for 2h;

upstream raw materials:

bromobenzene

N₅-methoxy-N₅-methyl-(2,4-difluorophenyl)-3,4-diazatricyclo[5.2.1.0(2,6)]deca-2⁽⁶⁾,4-dien-5-carboxamide

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