Hex-2-enoic anhydride

Base Information

• Chemical Name: Hex-2-enoic anhydride
• CAS No.: 14316-60-0
• Molecular Formula: C12H18 O3
• Molecular Weight: 210.273
• Hs Code.: 2916190090
• DSSTox Substance ID: DTXSID80708491
• Mol file: 14316-60-0.mol

Synonyms:Hex-2-enoic anhydride;SCHEMBL9196528;DTXSID80708491

Chemical Property of Hex-2-enoic anhydride

Chemical Property:

• Refractive Index: 1.468
• PSA: 43.37000
• LogP: 2.76880
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 8
• Exact Mass: 210.125594432
• Heavy Atom Count: 15
• Complexity: 226

Purity/Quality:

99% ^*data from raw suppliers

2-HEXENOIC ANHYDRIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCC=CC(=O)OC(=O)C=CCCC

Technology Process of Hex-2-enoic anhydride

There total 2 articles about Hex-2-enoic anhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-hexenoic acid (1191-04-4) → hex-2-enoic acid anhydride (14316-60-0)

Guidance literature:

With bis(trichloromethyl) carbonate; triethylamine; In ethyl acetate; at 0 - 25 ℃; for 0.416667h; Inert atmosphere;

DOI:10.1021/acs.orglett.0c02266

Reference yield:

hex-2-enoyl chloride (18802-95-4) + Sodium; (Z)-hex-2-enoate (105801-79-4) → hex-2-enoic acid anhydride (14316-60-0)

Guidance literature:

In benzene;

Reference yield:

hex-2-enoic acid anhydride (14316-60-0) → trans-2-pentenal (1576-87-0)

Guidance literature:

With pyridine N-oxide; In chlorobenzene;

upstream raw materials:

hex-2-enoyl chloride

Sodium; (Z)-hex-2-enoate

2-hexenoic acid

Downstream raw materials:

trans-2-pentenal