DL-PHENYLALANINE-2-D1

Base Information

• Chemical Name: DL-PHENYLALANINE-2-D1
• CAS No.: 14246-24-3
• Molecular Formula: C9H10 D N O2
• Molecular Weight: 166.184
• Mol file: 14246-24-3.mol

Synonyms:Alanine-2-d,phenyl-, DL- (8CI); DL-Phenylalanine-a-d

Chemical Property of DL-PHENYLALANINE-2-D1

Chemical Property:

• PSA: 63.32000
• LogP: 1.34130

Purity/Quality:

99% ^*data from raw suppliers

DL-Phenylalanine-2-d1 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: DL-Phenylalanine-2-d1 (CAS# 14246-24-3) is a useful isotopically labeled research compound.

Technology Process of DL-PHENYLALANINE-2-D1

There total 4 articles about DL-PHENYLALANINE-2-D1 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

dl-β-phenyl-α-alanine, potassium salt (55184-83-3) → DL-<α-2H>Phenylalanine (14246-24-3)

Guidance literature:

With potassium deuteroxide; water-d2; pyridoxal 5'-phosphate; for 2h; Heating; other catalyst: pyridoxal hydrochloride;

DOI:10.1021/jo00189a037

Reference yield: 70.0%

Phenylalanine (150-30-1,25191-15-5,658-69-5,67675-33-6) → DL-<α-2H>Phenylalanine (14246-24-3)

Guidance literature:

Phenylalanine; With deuteroacetic acid; salicylaldehyde; at 100 ℃; for 1h;

With water-d2; for 0.25h;

DOI:10.1021/ja1012917

Reference yield: 68.0%

L-phenylalanine (63-91-2,25191-15-5,658-69-5,67675-33-6) → DL-<α-2H>Phenylalanine (14246-24-3)

Guidance literature:

With deuteroacetic acid; salicylaldehyde; at 100 ℃; for 1h;

DOI:10.1002/(SICI)1099-1344(200004)43:5<449::AID-JLCR331>3.0.CO;2-0

upstream raw materials:

dl-β-phenyl-α-alanine, potassium salt

L-phenylalanine

Phenylalanine

Downstream raw materials:

N,N-phthaloyl-DL-[α2H]-phenylalanine

Refernces

• 1、 Moozeh, Kimia,So, Soon Mog,Chin, Jik. "Catalytic Stereoinversion of L -Alanine to Deuterated D -Alanine". . p. 9381 - 9385. Retrieved 2015/08/06.
• 2、 -. "METHOD FOR OBTAINING OPTICALLY PURE AMINO ACIDS". Page/Page column 10. . Retrieved 2012/02/14.