N-[2-[[2-(dimethylamino)phenyl]ethynyl]-1-cyclopentenyl]-N'-phenylcarbodiimide

Base Information

Chemical Name:N-[2-[[2-(dimethylamino)phenyl]ethynyl]-1-cyclopentenyl]-N'-phenylcarbodiimide
CAS No.:588700-15-6
Molecular Formula:C₂₂H₂₁N₃
Molecular Weight:327.429
Hs Code.:

Synonyms:N-[2-[[2-(dimethylamino)phenyl]ethynyl]-1-cyclopentenyl]-N'-phenylcarbodiimide

Suppliers and Price of N-[2-[[2-(dimethylamino)phenyl]ethynyl]-1-cyclopentenyl]-N'-phenylcarbodiimide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-[2-[[2-(dimethylamino)phenyl]ethynyl]-1-cyclopentenyl]-N'-phenylcarbodiimide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-[2-[[2-(dimethylamino)phenyl]ethynyl]-1-cyclopentenyl]-N'-phenylcarbodiimide

There total 9 articles about N-[2-[[2-(dimethylamino)phenyl]ethynyl]-1-cyclopentenyl]-N'-phenylcarbodiimide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 588700-10-1
N-[2-[[2-(dimethylamino)phenyl]ethynyl]-1-cyclopentenyl]-N'-phenylurea

: 588700-15-6
N-[2-[[2-(dimethylamino)phenyl]ethynyl]-1-cyclopentenyl]-N'-phenylcarbodiimide

Guidance literature:: With triethylamine; dibromotriphenylphosphorane; In dichloromethane; at 20 ℃; for 1h;
DOI:10.1021/jo020760n

Reference yield:

: 698-02-2
N,N-dimethyl-o-iodoaniline

: 588700-15-6
N-[2-[[2-(dimethylamino)phenyl]ethynyl]-1-cyclopentenyl]-N'-phenylcarbodiimide

Guidance literature:: Multi-step reaction with 7 steps

1: 95 percent / Et₃N; Pd(PPh₃)2Cl₂; CuI / dimethylformamide / 2 h / 20 °C

2: 98 percent / aq. NaOH / diethyl ether; methanol / 0.17 h / 20 °C

3: 91 percent / i-Pr₂NEt; Pd(PPh₃)2Cl₂; CuI / dimethylformamide / 2 h / 20 °C

4: 85 percent / aq. NaOH / tetrahydrofuran / 16 h / 70 °C

5: 87 percent / Et₃N; diphenyl phosphorazidate (DPPA) / benzene / 6 h / 20 °C

6: 76 percent / CH₂Cl₂ / 8 h / 20 °C

7: 50 percent / Et₃N; dibromotriphenylphosphorane / CH₂Cl₂ / 1 h / 20 °C

With bis-triphenylphosphine-palladium(II) chloride; sodium hydroxide; copper(l) iodide; diphenyl phosphoryl azide; triethylamine; N-ethyl-N,N-diisopropylamine; dibromotriphenylphosphorane; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; N,N-dimethyl-formamide; benzene;
DOI:10.1021/jo020760n

Reference yield:

: 122539-74-6
2-trifluoromethanesulfonyloxy-cyclopent-1-enecarboxylic acid ethyl ester

: 588700-15-6
N-[2-[[2-(dimethylamino)phenyl]ethynyl]-1-cyclopentenyl]-N'-phenylcarbodiimide

Guidance literature:: Multi-step reaction with 5 steps

1: 91 percent / i-Pr₂NEt; Pd(PPh₃)2Cl₂; CuI / dimethylformamide / 2 h / 20 °C

2: 85 percent / aq. NaOH / tetrahydrofuran / 16 h / 70 °C

3: 87 percent / Et₃N; diphenyl phosphorazidate (DPPA) / benzene / 6 h / 20 °C

4: 76 percent / CH₂Cl₂ / 8 h / 20 °C

5: 50 percent / Et₃N; dibromotriphenylphosphorane / CH₂Cl₂ / 1 h / 20 °C

With bis-triphenylphosphine-palladium(II) chloride; sodium hydroxide; copper(l) iodide; diphenyl phosphoryl azide; triethylamine; N-ethyl-N,N-diisopropylamine; dibromotriphenylphosphorane; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; benzene;
DOI:10.1021/jo020760n