6α-benzyl naltrexamine

Base Information

Chemical Name:6α-benzyl naltrexamine
CAS No.:1257541-94-8
Molecular Formula:C₂₇H₃₂N₂O₃
Molecular Weight:432.563
Hs Code.:

Synonyms:6α-benzyl naltrexamine

Suppliers and Price of 6α-benzyl naltrexamine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6α-benzyl naltrexamine

Chemical Property:

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Technology Process of 6α-benzyl naltrexamine

There total 4 articles about 6α-benzyl naltrexamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 16590-41-3
Naltrexone

: 100-46-9
benzylamine

: 1257541-94-8
6α-benzyl naltrexamine

Guidance literature:: Naltrexone; benzylamine; With formic acid; triethylamine; [RhCl₂(p-cymene)]2; In acetonitrile; at 25 ℃; for 72h;

With ammonium hydroxide; In water; acetonitrile; at 20 ℃; for 18h; pH=9.3;

Reference yield:

: 796876-15-8
C₂₇H₃₀N₂O₃

: 1257541-94-8
6α-benzyl naltrexamine

Guidance literature:: With sodium tetrahydroborate; In ethanol;
DOI:10.1021/jm801272c

Reference yield:

: 100-46-9
benzylamine

: 1257541-94-8
6α-benzyl naltrexamine

Guidance literature:: Multi-step reaction with 2 steps

1: toluene-4-sulfonic acid / benzene / 10 h / Reflux; Dean-Stark; Inert atmosphere

2: sodium tetrahydroborate; ethanol / Molecular sieve; Inert atmosphere

With sodium tetrahydroborate; ethanol; toluene-4-sulfonic acid; In benzene;