(E,S)-1-acetoxy-2-methyl-1-phenylsulfonyl-3-phenyl-2-propene

Base Information

• Chemical Name: (E,S)-1-acetoxy-2-methyl-1-phenylsulfonyl-3-phenyl-2-propene
• CAS No.: 283179-33-9
• Molecular Formula: C₁₈H₁₈O₄S
• Molecular Weight: 330.405
• Mol file: 283179-33-9.mol

Synonyms:(E,S)-1-acetoxy-2-methyl-1-phenylsulfonyl-3-phenyl-2-propene

Chemical Property of (E,S)-1-acetoxy-2-methyl-1-phenylsulfonyl-3-phenyl-2-propene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E,S)-1-acetoxy-2-methyl-1-phenylsulfonyl-3-phenyl-2-propene

There total 3 articles about (E,S)-1-acetoxy-2-methyl-1-phenylsulfonyl-3-phenyl-2-propene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

sodium benzenesulfonate (873-55-2) + (E)-1,1-diacetoxy-2-methyl-3-phenyl-2-propene (283179-25-9) → (E,S)-1-acetoxy-2-methyl-1-phenylsulfonyl-3-phenyl-2-propene (283179-33-9)

Guidance literature:

With bis(η3-allyl-μ-chloropalladium(II)); tetrahexylammonium bromide; (1R,2R)-1,2-bis[(2-diphenylphosphanyl)benzoylamino]cyclohexane; In dichloromethane; water; at 20 ℃; for 24h;

DOI:10.1021/ja000627h

Reference yield:

sodium benzenesulfonate (873-55-2) + (E)-1,1-diacetoxy-2-methyl-3-phenyl-2-propene (283179-25-9) → (E,S)-1-acetoxy-2-methyl-1-phenylsulfonyl-3-phenyl-2-propene (283179-33-9) + (E,R)-1-acetoxy-2-methyl-1-phenylsulfonyl-3-phenyl-2-propene (885223-85-8)

Guidance literature:

With water; tetramethylammonium bromide; [(η-C3H5PdCl)2]; In dichloromethane; at 20 ℃; for 24h; Title compound not separated from byproducts.;

DOI:10.1002/chem.200500919

Reference yield:

α-methyl-trans-cinnamaldehyde (15174-47-7) → (E,S)-1-acetoxy-2-methyl-1-phenylsulfonyl-3-phenyl-2-propene (283179-33-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 83 percent / FeCl₃ / CH₂Cl₂ / 2 h / 0 °C

2: tetramethylammonium bromide; (S,S)-1,2-di(o-HNCOC6H4-PPh2)cyclohexane; H2O / [(η-C3H5PdCl)2] / CH2Cl2 / 24 h / 20 °C

With water; tetramethylammonium bromide; iron(III) chloride; [(η-C3H5PdCl)2]; In dichloromethane;

DOI:10.1002/chem.200500919

upstream raw materials:

sodium benzenesulfonate

(E)-1,1-diacetoxy-2-methyl-3-phenyl-2-propene

α-methyl-trans-cinnamaldehyde