6-METHYLAZULENE

Base Information

• Chemical Name: 6-METHYLAZULENE
• CAS No.: 1654-52-0
• Molecular Formula: C11H10
• Molecular Weight: 142.2
• Mol file: 1654-52-0.mol

Synonyms:6-Methylazulene

Chemical Property of 6-METHYLAZULENE

Chemical Property:

• Vapor Pressure: 0.0523mmHg at 25°C
• Melting Point: 82 °C
• Boiling Point: 242.6°Cat760mmHg
• Flash Point: 93.6°C
• PSA: 0.00000
• Density: 1.016g/cm³
• LogP: 3.09980

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-METHYLAZULENE

There total 21 articles about 6-METHYLAZULENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

N-butyl-4-methylpyridinium bromide (65350-59-6) + cyclopenta-1,3-diene (542-92-7,25568-84-7,7313-32-8) → 6-methylazulene (1654-52-0)

Guidance literature:

cyclopenta-1,3-diene; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 ℃; for 0.75h; Inert atmosphere;

N-butyl-4-methylpyridinium bromide; In N,N-dimethyl-formamide; mineral oil; at 25 - 200 ℃; for 0.333333h; Inert atmosphere; Microwave irradiation;

DOI:10.1021/acs.orglett.7b00259

Reference yield: 22.0%

6-methyl-1,2,3,4-tetrahydroazulen-1-ol (52345-26-3) → 6-methylazulene (1654-52-0)

Guidance literature:

palladium on activated charcoal; In hexane; benzene; at 445 ℃;

DOI:10.1021/ja00540a023

Reference yield:

6-Methyl-3,4-dihydroazulen-1(2H)-one (52345-25-2) → 6-methylazulene (1654-52-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / aluminum hydride / tetrahydrofuran / 0 °C

2: 22 percent / 10percent Pd/C / benzene; hexane / 445 °C

With aluminium hydride; palladium on activated charcoal; In tetrahydrofuran; hexane; benzene;

DOI:10.1021/ja00540a023

upstream raw materials:

1-ethyl-4-methylpyridin-1-ium bromide

cyclopenta-1,3-diene

N-butyl-4-methylpyridinium bromide

6-methyl-1,2,3,4-tetrahydroazulen-1-ol

Downstream raw materials:

6-phenylazulene

6-(4-Biphenylyl)-azulen

6-Benzylbenzazulen

6-Phenylbenzazulen