(2S,3S)-3-(t-Boc-amino)-4-cyclohexyl-2-hydroxy-1-(isopropylthio)butane

Base Information

• Chemical Name: (2S,3S)-3-(t-Boc-amino)-4-cyclohexyl-2-hydroxy-1-(isopropylthio)butane
• CAS No.: 110206-06-9
• Molecular Formula: C₁₈H₃₅NO₃S
• Molecular Weight: 345.547
• Mol file: 110206-06-9.mol

Synonyms:(2S,3S)-3-(t-Boc-amino)-4-cyclohexyl-2-hydroxy-1-(isopropylthio)butane

Chemical Property of (2S,3S)-3-(t-Boc-amino)-4-cyclohexyl-2-hydroxy-1-(isopropylthio)butane

Chemical Property:

Purity/Quality:

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Technology Process of (2S,3S)-3-(t-Boc-amino)-4-cyclohexyl-2-hydroxy-1-(isopropylthio)butane

There total 1 articles about (2S,3S)-3-(t-Boc-amino)-4-cyclohexyl-2-hydroxy-1-(isopropylthio)butane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

(2R,3S)-3-(t-butoxycarbonylamino)-4-cyclohexyl-1,2-epoxybutane (107202-61-9) + 2-propanethiol (75-33-2) → (2S,3S)-3-(t-Boc-amino)-4-cyclohexyl-2-hydroxy-1-(isopropylthio)butane (110206-06-9) + (2R,3S)-3-(t-Boc-amino)-4-cyclohexyl-2-hydroxy-1-(isopropylthio)butane (110206-07-0)

Guidance literature:

With triethylamine; In methanol; for 2h; Heating;

DOI:10.1021/jm00394a035

upstream raw materials:

(2R,3S)-3-(t-butoxycarbonylamino)-4-cyclohexyl-1,2-epoxybutane

2-propanethiol