3-(1-methyl-1H-pyrazol-4-yl)-5-(4-methylcyclohex-1-enyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine

Base Information

• Chemical Name: 3-(1-methyl-1H-pyrazol-4-yl)-5-(4-methylcyclohex-1-enyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine
• CAS No.: 1046830-19-6
• Molecular Formula: C₂₄H₂₄N₄O₂S
• Molecular Weight: 432.546
• Mol file: 1046830-19-6.mol

Synonyms:3-(1-methyl-1H-pyrazol-4-yl)-5-(4-methylcyclohex-1-enyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine

Chemical Property of 3-(1-methyl-1H-pyrazol-4-yl)-5-(4-methylcyclohex-1-enyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 3-(1-methyl-1H-pyrazol-4-yl)-5-(4-methylcyclohex-1-enyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine

There total 1 articles about 3-(1-methyl-1H-pyrazol-4-yl)-5-(4-methylcyclohex-1-enyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

(4-methylcyclohex-1-en-1-yl)boronic acid (850567-92-9) + 5-bromo-3-(1-methyl-1H-pyrazol-4-yl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine (923584-11-6) → 3-(1-methyl-1H-pyrazol-4-yl)-5-(4-methylcyclohex-1-enyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine (1046830-19-6)

Guidance literature:

With sodium carbonate; lithium chloride; bis-triphenylphosphine-palladium(II) chloride; In ethanol; water; toluene; at 105 - 110 ℃; for 8h;

Reference yield: 69.0%

3-(1-methyl-1H-pyrazol-4-yl)-5-(4-methylcyclohex-1-enyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine (1046830-19-6) → 3-(1-methyl-1H-pyrazol-4-yl)-5-(4-methylcyclohex-1-enyl)-1H-pyrrolo[2,3-b]pyridine (1046828-77-6)

Guidance literature:

3-(1-methyl-1H-pyrazol-4-yl)-5-(4-methylcyclohex-1-enyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; With sodium hydroxide; ethanol; water; at 80 ℃; for 0.666667h;

With water; sodium hydrogencarbonate;

upstream raw materials:

(4-methylcyclohex-1-en-1-yl)boronic acid

5-bromo-3-(1-methyl-1H-pyrazol-4-yl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine

Downstream raw materials:

3-(1-methyl-1H-pyrazol-4-yl)-5-(4-methylcyclohex-1-enyl)-1H-pyrrolo[2,3-b]pyridine