Androst-5-ene-3,17-diol-17-propanoic acid lactone

Base Information

• Chemical Name: Androst-5-ene-3,17-diol-17-propanoic acid lactone
• CAS No.: 14009-58-6
• Molecular Formula: C₂₂H₃₂O₃
• Molecular Weight: 344.494
• Mol file: 14009-58-6.mol

Synonyms:3,17-Dihydroxyandrost-5-ene-17-propionic acid lactone;Androst-5-ene-3,17-diol-17-propanoic acid lactone

Chemical Property of Androst-5-ene-3,17-diol-17-propanoic acid lactone

Chemical Property:

• Melting Point: 237-241 °C
• Boiling Point: 517.4±50.0 °C(Predicted)
• PKA: 15.02±0.60(Predicted)
• Density: 1.17±0.1 g/cm3(Predicted)

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Androst-5-ene-3,17-diol-17-propanoic acid lactone

There total 3 articles about Androst-5-ene-3,17-diol-17-propanoic acid lactone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ C22H32O3 (13934-61-7,14009-58-6)

Guidance literature:

Epoxid (2), Essigsaeure, n-Butyl-lithium;

DOI:10.1021/jo00977a013

Reference yield:

→ C22H32O3 (13934-61-7,14009-58-6)

Guidance literature:

aus 2, Vorschrift B;

Reference yield:

→ 3β,17α-Dihydroxy-21-carboxy-pregnen-5-lacton (13934-61-7,14009-58-6)

Guidance literature:

3β,17α,20-Trihydroxy-21-acetoxymethyl-20-methansulfonylpregn-5-en-3β-acetat, CH2Cl2: 1) Br2 (8grad) 2) CrO3, aq.AcOH (15h 20grad) 3) Zn-staub, MeOH 4) Zn-staub, sd.Eg. 5) konz.HCl (2h); neben 17α-Hydroxy-21-carboxypregn-4-en-3-on-lacton;

DOI:10.1021/jo01050a547

Downstream raw materials:

C₂₂H₃₂BrClO₃

5α-bromo-6β-chloro-3β,17α-dihydroxypregnane-21-carboxylic acid χ-lactone

canrenone

Refernces