1,2,3,4-Tetrahydro-1,5-naphthyridine

Base Information

Chemical Name:1,2,3,4-Tetrahydro-1,5-naphthyridine
CAS No.:13993-61-8
Molecular Formula:C8H10N2
Molecular Weight:134.181
Hs Code.:2933990090
European Community (EC) Number:826-595-4
DSSTox Substance ID:DTXSID60426060
Nikkaji Number:J893.345F
Wikidata:Q82239045
Mol file:13993-61-8.mol

Synonyms:1,2,3,4-tetrahydro-1,5-naphthyridine;13993-61-8;1,2,3,4-tetrahydro-[1,5]naphthyridine;CMLDBU00003583;1,5-NAPHTHYRIDINE, 1,2,3,4-TETRAHYDRO-;MFCD08444439;tetrahydro 1,5-naphthyridine;SCHEMBL307955;DTXSID60426060;OALXTMWCXNPUKJ-UHFFFAOYSA-N;AMY20041;AKOS009101721;AB45266;CS-W006541;1,2,3,4-tetrahydro[1,5]naphthyridine;SY011552;1,5-Naphthyridine,1,2,3,4-tetrahydro-;FT-0690791;EN300-25624;A807603;Z212053854

Suppliers and Price of 1,2,3,4-Tetrahydro-1,5-naphthyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1,2,3,4-tetrahydro-1,5-naphthyridine
25mg
$ 45.00

TRC
1,2,3,4-tetrahydro-1,5-naphthyridine
50mg
$ 90.00

SynQuest Laboratories
1,2,3,4-Tetrahydro-1,5-naphthyridine 97%
250 mg
$ 224.00

SynQuest Laboratories
1,2,3,4-Tetrahydro-1,5-naphthyridine 97%
1 g
$ 512.00

Matrix Scientific
1,2,3,4-Tetrahydro-1,5-naphthyridine 97%
5g
$ 1980.00

Matrix Scientific
1,2,3,4-Tetrahydro-1,5-naphthyridine 97%
1g
$ 742.00

Labseeker
1,2,3,4-tetrahydro-1,5-naphthyridine 95
1g
$ 431.00

J&W Pharmlab
1,2,3,4-Tetrahydro-[1,5]naphthyridine 97%
1g
$ 150.00

J&W Pharmlab
1,2,3,4-Tetrahydro-[1,5]naphthyridine 97%
5g
$ 450.00

Crysdot
1,2,3,4-Tetrahydro-1,5-naphthyridine 97%
5g
$ 446.00

Total 14 raw suppliers

Chemical Property of 1,2,3,4-Tetrahydro-1,5-naphthyridine

Chemical Property:

Vapor Pressure:0.00926mmHg at 25°C
Melting Point:107-109 °C
Refractive Index:1.548
Boiling Point:265.3 °C at 760 mmHg
PKA:7.24±0.20(Predicted)
Flash Point:114.2 °C
PSA：24.92000
Density:1.068 g/cm³
LogP:1.57770
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:134.084398327
Heavy Atom Count:10
Complexity:114

Purity/Quality:

97% ^*data from raw suppliers

1,2,3,4-tetrahydro-1,5-naphthyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2=C(C=CC=N2)NC1
Uses 1,2,3,4-Tetrahydro-1,5-naphthyridine can be used as SHP2 inhibitors to treat diseases.

Technology Process of 1,2,3,4-Tetrahydro-1,5-naphthyridine

There total 8 articles about 1,2,3,4-Tetrahydro-1,5-naphthyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 254-79-5
1,5-naphthyridine

: 13993-61-8
1.1,2,3,4-tetrahydro-1,5-naphthyridine

Guidance literature:: With hydrogen; cobalt(II) diacetate tetrahydrate; zinc; In water; at 100 ℃; for 15h; under 22502.3 Torr; Sealed tube; Autoclave;
DOI:10.1055/a-1654-3302

Reference yield: 87.0%

: 198549-21-2
3-(3-(2-phenylimidazol-1-yl)propyl)-1,2,4-triazine

: 13993-61-8
1.1,2,3,4-tetrahydro-1,5-naphthyridine

Guidance literature:: With 2,6-di-tert-butyl-4-methyl-phenol; triisopropylbenzene; at 232 ℃; for 3h;
DOI:10.1021/jo040193z

Reference yield: 48.5%

: 13993-61-8
1.1,2,3,4-tetrahydro-1,5-naphthyridine

Guidance literature:: With bis(1,5-cyclooctadiene)diiridium(I) dichloride; phenylsilane; In methanol; at 45 ℃; for 24h; Inert atmosphere; Sealed tube;