Technology Process of 3-(aminomethyl)-1-N-(3-(N'-(3-isopropylureido))benzyl)-2,3,4,5-tetrahydro-1H-1-benzazepin-2-one
There total 4 articles about 3-(aminomethyl)-1-N-(3-(N'-(3-isopropylureido))benzyl)-2,3,4,5-tetrahydro-1H-1-benzazepin-2-one which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride; hydrogen;
palladium on activated charcoal;
In
ethanol;
under 2942.03 Torr;
DOI:10.1021/jm990044m
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 97 percent / tetra-n-butylammonium bromide, KOH / tetrahydrofuran / 2 h / Ambient temperature
2: 59 percent / n-Bu4NBr / dimethylsulfoxide / 9 h / 115 °C
3: 67 percent / 12N aq. HCl, H2 / 10 percent Pd/C / ethanol / 2942.03 Torr
With
hydrogenchloride; potassium hydroxide; tetrabutylammomium bromide; hydrogen;
palladium on activated charcoal;
In
tetrahydrofuran; ethanol; dimethyl sulfoxide;
DOI:10.1021/jm990044m
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 97 percent / tetra-n-butylammonium bromide, KOH / tetrahydrofuran / 2 h / Ambient temperature
2: 59 percent / n-Bu4NBr / dimethylsulfoxide / 9 h / 115 °C
3: 67 percent / 12N aq. HCl, H2 / 10 percent Pd/C / ethanol / 2942.03 Torr
With
hydrogenchloride; potassium hydroxide; tetrabutylammomium bromide; hydrogen;
palladium on activated charcoal;
In
tetrahydrofuran; ethanol; dimethyl sulfoxide;
DOI:10.1021/jm990044m
