Technology Process of 7-Oxo-8-(phenylsulfonyl)-5,6,7,8-tetrahydroquinoline
There total 7 articles about 7-Oxo-8-(phenylsulfonyl)-5,6,7,8-tetrahydroquinoline which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium tert-butylate;
In
tetrahydrofuran;
for 1h;
Ambient temperature;
DOI:10.1021/jo00323a016
- Guidance literature:
-
Multi-step reaction with 5 steps
1: KMnO4 / methanol; H2O / 0.5 h / Ambient temperature
2: 62 percent / NBS, azobis(isobutyronitrile) / CCl4 / 2 h / Heating; Irradiation
3: 1.) LDA, HMPT / 1.) THF, 0 deg C, 1 h, 2.) -78 deg C, 0.5 h
4: Raney nickel / ethanol; acetone / 1 h / 60 °C
5: 71 percent / t-BuOK / tetrahydrofuran / 1 h / Ambient temperature
With
N,N,N,N,N,N-hexamethylphosphoric triamide; potassium permanganate; N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); potassium tert-butylate; nickel; lithium diisopropyl amide;
In
tetrahydrofuran; methanol; tetrachloromethane; ethanol; water; acetone;
DOI:10.1021/jo00323a016
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 62 percent / NBS, azobis(isobutyronitrile) / CCl4 / 2 h / Heating; Irradiation
2: 1.) LDA, HMPT / 1.) THF, 0 deg C, 1 h, 2.) -78 deg C, 0.5 h
3: Raney nickel / ethanol; acetone / 1 h / 60 °C
4: 71 percent / t-BuOK / tetrahydrofuran / 1 h / Ambient temperature
With
N,N,N,N,N,N-hexamethylphosphoric triamide; N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); potassium tert-butylate; nickel; lithium diisopropyl amide;
In
tetrahydrofuran; tetrachloromethane; ethanol; acetone;
DOI:10.1021/jo00323a016
