2-(2-chloro-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)benzyl)-7-methyl-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one

Base Information

Chemical Name:2-(2-chloro-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)benzyl)-7-methyl-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one
CAS No.:1334297-55-0
Molecular Formula:C₂₀H₂₂ClN₃O₆
Molecular Weight:435.864
Hs Code.:

Synonyms:2-(2-chloro-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)benzyl)-7-methyl-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one

Suppliers and Price of 2-(2-chloro-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)benzyl)-7-methyl-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(2-chloro-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)benzyl)-7-methyl-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-(2-chloro-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)benzyl)-7-methyl-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one

There total 8 articles about 2-(2-chloro-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)benzyl)-7-methyl-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1613149-91-9
C₂₈H₃₀ClN₃O₁₀

: 1334297-55-0
2-(2-chloro-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)benzyl)-7-methyl-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one

Guidance literature:: With potassium carbonate; In methanol; at 20 ℃; for 18h;
DOI:10.1016/j.bmc.2014.04.036

Reference yield:

: 866605-98-3
C₃₇H₄₃ClO₁₀Si

: 1334297-55-0
2-(2-chloro-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)benzyl)-7-methyl-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one

Guidance literature:: Multi-step reaction with 3 steps

1: acetic acid; tetrabutyl ammonium fluoride / tetrahydrofuran / 0 - 20 °C

2: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 15 h / 20 °C / Inert atmosphere

3: potassium carbonate / methanol / 18 h / 20 °C

With tetrabutyl ammonium fluoride; potassium carbonate; acetic acid; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; methanol; 2: |Mitsunobu Displacement;
DOI:10.1016/j.bmc.2014.04.036

Reference yield:

: 866605-96-1
(3R,4S,5S,6R)-2-(3-((tert-butyldiphenylsilyloxy)methyl)-4-chlorophenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol

: 1334297-55-0
2-(2-chloro-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)benzyl)-7-methyl-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one

Guidance literature:: Multi-step reaction with 5 steps

1: triethylsilane; boron trifluoride diethyl etherate / dichloromethane / 2 h / 0 °C

2: pyridine; dmap / chloroform / 20 °C

3: acetic acid; tetrabutyl ammonium fluoride / tetrahydrofuran / 0 - 20 °C

4: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 15 h / 20 °C / Inert atmosphere

5: potassium carbonate / methanol / 18 h / 20 °C

With pyridine; triethylsilane; dmap; boron trifluoride diethyl etherate; tetrabutyl ammonium fluoride; potassium carbonate; acetic acid; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; methanol; dichloromethane; chloroform; 4: |Mitsunobu Displacement;
DOI:10.1016/j.bmc.2014.04.036